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RAX2 Rax2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850773, updated on 9-Dec-2024

Summary

Official Symbol
RAX2
Official Full Name
Rax2p
Primary source
SGD:S000004074
Locus tag
YLR084C
See related
AllianceGenome:SGD:S000004074; FungiDB:YLR084C; VEuPathDB:YLR084C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in axial cellular bud site selection; bipolar cellular bud site selection; and protein localization. Located in cellular bud neck and cellular bud scar. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See RAX2 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (296589..300251, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Srl2p Neighboring gene Emp70p Neighboring gene Arp6p Neighboring gene condensin subunit SMC4

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in axial cellular bud site selection IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in bipolar cellular bud site selection IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in bipolar cellular bud site selection IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular bud site selection IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cellular bud neck HDA PubMed 
is_active_in cellular bud neck IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cellular bud neck IDA
Inferred from Direct Assay
more info
PubMed 
located_in cellular bud neck IEA
Inferred from Electronic Annotation
more info
 
is_active_in cellular bud scar IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cellular bud scar IDA
Inferred from Direct Assay
more info
PubMed 
located_in cellular bud tip IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane of growing cell tip IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Rax2p
NP_013185.1
  • Protein required for the maintenance of bud site selection; localizes; localization to the bud neck and previous sites of cell division (bud scars; cytokinesis remnants (CRMs)) is interdependent with Rax2p; required with Rax1p to anchor both Nba1p and Nis1p to CRMs where a Cdc42p inhibitory zone is established preventing repolarization of cells at previous division sites; RAX2 mRNA stability is regulated by Mpt5p; predicted type I membrane-spanning protein; N-glycosylated

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    296589..300251 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181971.1NP_013185.1  TPA: Rax2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013185.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VY84, Q12465
    UniProtKB/TrEMBL
    A7A0Y8, B3LT52, B5VN16
    Conserved Domains (1) summary
    pfam12768
    Location:9761213
    Rax2; Cortical protein marker for cell polarity