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GIP4 protein phosphatase regulator GIP4 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851202, updated on 9-Dec-2024

Summary

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Official Symbol
GIP4
Official Full Name
protein phosphatase regulator GIP4
Primary source
SGD:S000000029
Locus tag
YAL031C
See related
AllianceGenome:SGD:S000000029; FungiDB:YAL031C; VEuPathDB:YAL031C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
FUN21
Summary
Enables protein phosphatase 1 binding activity and protein phosphatase regulator activity. Involved in chromosome segregation. Located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See GIP4 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_001133.9 (84749..87031, complement)

Chromosome I - NC_001133.9Genomic Context describing neighboring genes Neighboring gene RNA-binding protein POP5 Neighboring gene mRNA splicing protein PRP45 Neighboring gene SNAP receptor SNC1 Neighboring gene myosin 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001133.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular analysis of Saccharomyces cerevisiae chromosome I: identification of additional transcribed regions and demonstration that some encode essential functions. Diehl BE, et al. Genetics, 1991 Feb. PMID 1825988, Free PMC Article
  2. Yeast ARL1 encodes a regulator of K+ influx. Munson AM, et al. J Cell Sci, 2004 May 1. PMID 15126631
  3. Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/aurora protein kinase by redistributing Glc7. Pinsky BA, et al. Mol Cell Biol, 2006 Apr. PMID 16537909, Free PMC Article
  4. Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae. van Nues RW, et al. Genetics, 2001 Apr. PMID 11290703, Free PMC Article
  5. The nucleotide sequence of chromosome I from Saccharomyces cerevisiae. Bussey H, et al. Proc Natl Acad Sci U S A, 1995 Apr 25. PMID 7731988, Free PMC Article

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables protein phosphatase 1 binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein phosphatase 1 binding IEA
Inferred from Electronic Annotation
more info
  
enables protein phosphatase regulator activity IEA
Inferred from Electronic Annotation
more info
  
enables protein phosphatase regulator activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromosome segregation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein phosphatase regulator GIP4
NP_009371.1
  • Cytoplasmic protein that regulates protein phosphatase 1 Glc7p; protein overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; potential Cdc28p substrate

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001133.9 Reference assembly

    Range
    84749..87031 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178176.1 → NP_009371.1  TPA: protein phosphatase regulator GIP4 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009371.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VPI7, P39732
    UniProtKB/TrEMBL
    C7GPK4, C8Z3H1, N1P9T1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P39732.2

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