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ECM1 Ecm1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851240, updated on 4-Jan-2025

Summary

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Official Symbol
ECM1
Official Full Name
Ecm1p
Primary source
SGD:S000000055
Locus tag
YAL059W
See related
AllianceGenome:SGD:S000000055; FungiDB:YAL059W; VEuPathDB:YAL059W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in ribosomal large subunit export from nucleus. Located in nucleolus. Part of preribosome, large subunit precursor. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See ECM1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_001133.9 (36509..37147)

Chromosome I - NC_001133.9Genomic Context describing neighboring genes Neighboring gene putative dehydrogenase BDH2 Neighboring gene (R,R)-butanediol dehydrogenase Neighboring gene calnexin Neighboring gene Gpb2p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001133.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ecm11 is located in the cell nucleus throughout mitosis. Comino A, et al. Pflugers Arch, 2001. PMID 11678331
  2. Bcp1 Is the Nuclear Chaperone of Rpl23 in Saccharomyces cerevisiae. Ting YH, et al. J Biol Chem, 2017 Jan 13. PMID 27913624, Free PMC Article
  3. Coupling protein complex analysis to peptide based proteomics. Gao Q, et al. J Chromatogr A, 2010 Dec 3. PMID 21036361
  4. A ribosome-anchored chaperone network that facilitates eukaryotic ribosome biogenesis. Albanèse V, et al. J Cell Biol, 2010 Apr 5. PMID 20368619, Free PMC Article
  5. Structure of the Cdc48 segregase in the act of unfolding an authentic substrate. Cooney I, et al. Science, 2019 Aug 2. PMID 31249134, Free PMC Article

See all (52) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in ribosomal large subunit export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal large subunit export from nucleus IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of preribosome, large subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of preribosome, large subunit precursor IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Ecm1p
NP_009342.2
  • Pre-ribosomal factor involved in 60S ribosomal protein subunit export; associates with the pre-60S particle; shuttles between the nucleus and cytoplasm

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001133.9 Reference assembly

    Range
    36509..37147
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178201.2 → NP_009342.2  TPA: Ecm1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009342.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VPG0, E9P8V4, P39715
    UniProtKB/TrEMBL
    G2W8H4, N1P9T5
    Conserved Domains (1) summary
    pfam09135
    Location:31 → 152
    Alb1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P39715.2

Gene LinkOut

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