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YCX1 Ycx1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851321, updated on 4-Jan-2025

Summary

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Official Symbol
YCX1
Official Full Name
Ycx1p
Primary source
SGD:S000002365
Locus tag
YDL206W
See related
AllianceGenome:SGD:S000002365; FungiDB:YDL206W; VEuPathDB:YDL206W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable monoatomic cation transmembrane transporter activity. Acts upstream of or within calcineurin-mediated signaling. Located in fungal-type vacuole membrane. Is active in Golgi apparatus and endoplasmic reticulum. Orthologous to human SLC8B1 (solute carrier family 8 member B1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See YCX1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (90176..92464)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene snoRNA-binding protein NHP2 Neighboring gene nucleoporin GLE1 Neighboring gene hydroxymethylbilane synthase Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Ycx1 protein encoded by the yeast YDL206W gene plays a role in calcium and calcineurin signaling. Lee GM, et al. J Biol Chem, 2023 May. PMID 36965615, Free PMC Article
  2. An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae. Lesage G, et al. BMC Genet, 2005 Feb 16. PMID 15715908, Free PMC Article
  3. A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria. Lahiri S, et al. PLoS Biol, 2014 Oct. PMID 25313861, Free PMC Article
  4. Whi3, a developmental regulator of budding yeast, binds a large set of mRNAs functionally related to the endoplasmic reticulum. Colomina N, et al. J Biol Chem, 2008 Oct 17. PMID 18667435, Free PMC Article
  5. Saccharomyces cerevisiae Is Dependent on Vesicular Traffic between the Golgi Apparatus and the Vacuole When Inositolphosphorylceramide Synthase Aur1 Is Inactivated. Voynova NS, et al. Eukaryot Cell, 2015 Dec. PMID 26432633, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The Ycx1 protein encoded by the yeast YDL206W gene plays a role in calcium and calcineurin signaling.
    Title: The Ycx1 protein encoded by the yeast YDL206W gene plays a role in calcium and calcineurin signaling.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables monoatomic cation transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within calcineurin-mediated signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular calcium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in monoatomic cation transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic cation transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in fungal-type vacuole membrane HDA PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ycx1p
NP_010075.1
  • Protein involved in calcium-induced activation of calcineurin; homologous to proteins in Candida and Cryptococcus; YCX1 is not an essential protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    90176..92464
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180266.1 → NP_010075.1  TPA: Ycx1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010075.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRE8, Q12424
    UniProtKB/TrEMBL
    G2WBW1, N1P6F7
    Conserved Domains (1) summary
    COG0530
    Location:28 → 223
    ECM27; Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12424.1

Gene LinkOut

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