U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

AIT1 Ait1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851374, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
AIT1
Official Full Name
Ait1p
Primary source
SGD:S000002339
Locus tag
YDL180W
See related
AllianceGenome:SGD:S000002339; FungiDB:YDL180W; VEuPathDB:YDL180W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Acts upstream of or within negative regulation of TORC1 signaling. Located in fungal-type vacuole. Is active in fungal-type vacuole membrane. [provided by Alliance of Genome Resources, Dec 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See AIT1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (135896..137539)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene homocitrate synthase LYS20 Neighboring gene ATPase inhibitor Neighboring gene Pcl9p Neighboring gene D-lactate dehydrogenase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Ait1 regulates TORC1 signaling and localization in budding yeast. Wallace RL, et al. Elife, 2022 Sep 1. PMID 36047762, Free PMC Article
  2. Dissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes. Wuttke D, et al. PLoS Genet, 2012. PMID 22912585, Free PMC Article
  3. Regulation of stress response signaling by the N-terminal dishevelled/EGL-10/pleckstrin domain of Sst2, a regulator of G protein signaling in Saccharomyces cerevisiae. Burchett SA, et al. J Biol Chem, 2002 Jun 21. PMID 11940600
  4. Characterization of the interaction between Rfa1 and Rad24 in Saccharomyces cerevisiae. Piya G, et al. PLoS One, 2015. PMID 25719602, Free PMC Article
  5. Systematic genetic array analysis links the Saccharomyces cerevisiae SAGA/SLIK and NuA4 component Tra1 to multiple cellular processes. Hoke SM, et al. BMC Genet, 2008 Jul 10. PMID 18616809, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of TORC1 signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in fungal-type vacuole HDA PubMed 
located_in fungal-type vacuole membrane HDA PubMed 
is_active_in fungal-type vacuole membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in vacuolar membrane IEA
Inferred from Electronic Annotation
more info
  
located_in vacuole IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Ait1p
NP_010101.1
  • G protein-coupled receptor-like protein; involved in negatively regulating TORC1 activity; green fluorescent protein (GFP)-fusion protein localizes to the vacuole

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    135896..137539
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180240.1 → NP_010101.1  TPA: Ait1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010101.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRH2, Q12301
    UniProtKB/TrEMBL
    B3LH64, C8Z6C4, N1P8U3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12301.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools