U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

short-chain dehydrogenase/reductase [ Saccharomyces cerevisiae S288C ]

Gene ID: 851444, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Full Name
short-chain dehydrogenase/reductase
Primary source
SGD:S000002272
Locus tag
YDL114W
See related
AllianceGenome:SGD:S000002272; FungiDB:YDL114W; VEuPathDB:YDL114W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Orthologous to several human genes including DHRS3 (dehydrogenase/reductase 3); HSD17B11 (hydroxysteroid 17-beta dehydrogenase 11); and HSD17B13 (hydroxysteroid 17-beta dehydrogenase 13). [provided by Alliance of Genome Resources, Dec 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (255604..256530)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Nup84p Neighboring gene Iwr1p Neighboring gene Atg20p Neighboring gene tRNA (guanosine(18)-2'-O)-methyltransferase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Fungal BLAST and Model Organism BLASTP Best Hits: new comparison resources at the Saccharomyces Genome Database (SGD). Balakrishnan R, et al. Nucleic Acids Res, 2005 Jan 1. PMID 15608219, Free PMC Article
  2. Linking functionally related genes by sensitive and quantitative characterization of genetic interaction profiles. Decourty L, et al. Proc Natl Acad Sci U S A, 2008 Apr 15. PMID 18408161, Free PMC Article
  3. Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7. Logan MR, et al. BMC Genomics, 2008 Jul 15. PMID 18627629, Free PMC Article
  4. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549
  5. A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy. Srivas R, et al. Mol Cell, 2016 Aug 4. PMID 27453043, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
short-chain dehydrogenase/reductase
NP_010169.1
  • Putative short-chain dehydrogenase/reductase; YDL114W is not an essential gene

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    255604..256530
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180173.1 → NP_010169.1  TPA: short-chain dehydrogenase/reductase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010169.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRN6, Q07530
    UniProtKB/TrEMBL
    A6ZXL5, N1P5L3
    Conserved Domains (1) summary
    cd05339
    Location:40 → 282
    17beta-HSDXI-like_SDR_c; human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q07530.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.