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uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 851550, updated on 4-Jan-2025

Summary

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Official Full Name
uncharacterized protein
Primary source
SGD:S000002170
Locus tag
YDL012C
See related
AllianceGenome:SGD:S000002170; FungiDB:YDL012C; VEuPathDB:YDL012C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Located in plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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Location:
chromosome: IV
Exon count:
2
Sequence:
Chromosome: IV; NC_001136.10 (431108..431517, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene rRNA methyltransferase NOP1 Neighboring gene SUMO-targeted ubiquitin ligase complex subunit SLX5 Neighboring gene glutathione-disulfide reductase GRX6 Neighboring gene uncharacterized protein Neighboring gene anaphase promoting complex subunit 11

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Global investigation of protein-protein interactions in yeast Saccharomyces cerevisiae using re-occurring short polypeptide sequences. Pitre S, et al. Nucleic Acids Res, 2008 Aug. PMID 18586826, Free PMC Article
  2. Disruption and functional analysis of seven ORFs on chromosome IV: YDL057w, YDL012c, YDL010w, YDL009c, YDL008w (APC11), YDL005c (MED2) and YDL003w (MCD1). Smith KN, et al. Yeast, 1999 Sep 15. PMID 10487928
  3. CYSTM, a novel cysteine-rich transmembrane module with a role in stress tolerance across eukaryotes. Venancio TM, et al. Bioinformatics, 2010 Jan 15. PMID 19933165, Free PMC Article
  4. Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae. Beilharz T, et al. J Biol Chem, 2003 Mar 7. PMID 12514182
  5. Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast. Gupta R, et al. Mol Syst Biol, 2007. PMID 17551511, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in cellular bud HDA PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_010272.1
  • Tail-anchored plasma membrane protein with a conserved CYSTM module; possibly involved in response to stress; may contribute to non-homologous end-joining (NHEJ) based on ydl012c htz1 double null phenotype; YDL012C has a paralog, YBR016W, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    431108..431517 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180071.1 → NP_010272.1  TPA: uncharacterized protein YDL012C [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010272.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRX7, Q12489
    UniProtKB/TrEMBL
    A6ZXV6, B3LGR9, C7GW66, C8Z4Q7, G2WCE3, N1PAB1
    Conserved Domains (1) summary
    pfam12734
    Location:75 → 107
    CYSTM; Cysteine-rich TM module stress tolerance
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12489.1

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