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NGG1 histone acetyltransferase NGG1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851756, updated on 9-Dec-2024

Summary

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Official Symbol
NGG1
Official Full Name
histone acetyltransferase NGG1
Primary source
SGD:S000002583
Locus tag
YDR176W
See related
AllianceGenome:SGD:S000002583; FungiDB:YDR176W; VEuPathDB:YDR176W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
ADA3; SWI7
Summary
Contributes to histone acetyltransferase activity. Involved in chromatin organization. Part of ADA complex; SAGA complex; and SLIK (SAGA-like) complex. Orthologous to human TADA3 (transcriptional adaptor 3). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See NGG1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (814452..816560)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Hmo1p Neighboring gene mitochondrial 37S ribosomal protein RSM24 Neighboring gene E2 ubiquitin-conjugating protein UBC1 Neighboring gene succinate dehydrogenase membrane anchor subunit SDH4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The yeast Ada complex mediates the ligand-dependent activation function AF-2 of retinoid X and estrogen receptors. vom Baur E, et al. Genes Dev, 1998 May 1. PMID 9573045, Free PMC Article
  2. Expression and purification of recombinant yeast Ada2/Ada3/Gcn5 and Piccolo NuA4 histone acetyltransferase complexes. Barrios A, et al. Methods, 2007 Mar. PMID 17309836, Free PMC Article
  3. ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2. Piña B, et al. Mol Cell Biol, 1993 Oct. PMID 8413201, Free PMC Article
  4. Structure/functional properties of the yeast dual regulator protein NGG1 that are required for glucose repression. Brandl CJ, et al. J Biol Chem, 1996 Apr 19. PMID 8621592
  5. ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription. Marcus GA, et al. Mol Cell Biol, 1996 Jun. PMID 8649430, Free PMC Article

See all (161) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
contributes_to histone acetyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in chromatin organization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
  
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of ADA complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of SAGA complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SAGA complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of SLIK (SAGA-like) complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
histone acetyltransferase NGG1
NP_010461.3
  • Subunit of chromatin modifying histone acetyltransferase complexes; member of the ADA complex, the SAGA complex, and the SLIK complex; transcriptional regulator involved in glucose repression of Gal4p-regulated genes

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    814452..816560
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180483.3 → NP_010461.3  TPA: histone acetyltransferase NGG1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010461.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VSF8, P32494
    UniProtKB/TrEMBL
    B3LGA7, C7GN21
    Conserved Domains (1) summary
    pfam10198
    Location:506 → 648
    Ada3; Histone acetyltransferases subunit 3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32494.1

Gene LinkOut

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