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AMD2 putative amidase [ Saccharomyces cerevisiae S288C ]

Gene ID: 851829, updated on 9-Dec-2024

Summary

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Official Symbol
AMD2
Official Full Name
putative amidase
Primary source
SGD:S000002650
Locus tag
YDR242W
See related
AllianceGenome:SGD:S000002650; FungiDB:YDR242W; VEuPathDB:YDR242W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable indoleacetamide hydrolase activity. Predicted to be involved in amide catabolic process. Human ortholog(s) of this gene implicated in obesity and substance-related disorder. Orthologous to human FAAH (fatty acid amide hydrolase). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See AMD2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (946807..948456)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Snu56p Neighboring gene tRNA-Tyr Neighboring gene mRNA splicing protein PRP28 Neighboring gene Pex5p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of a putative amidase gene in yeast Saccharomyces cerevisiae. Chang TH, et al. Nucleic Acids Res, 1990 Dec 11. PMID 2263500, Free PMC Article
  2. The unfolded protein response is necessary but not sufficient to compensate for defects in disulfide isomerization. Kim JH, et al. J Biol Chem, 2009 Apr 17. PMID 19233841, Free PMC Article
  3. Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7. Logan MR, et al. BMC Genomics, 2008 Jul 15. PMID 18627629, Free PMC Article
  4. The S. cerevisiae m6A-reader Pho92 promotes timely meiotic recombination by controlling key methylated transcripts. Scutenaire J, et al. Nucleic Acids Res, 2023 Jan 25. PMID 35934316, Free PMC Article
  5. Association of yeast Upf1p with direct substrates of the NMD pathway. Johansson MJ, et al. Proc Natl Acad Sci U S A, 2007 Dec 26. PMID 18087042, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables amidase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in amide catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
putative amidase
NP_010528.3
  • Putative amidase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    946807..948456
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180550.3 → NP_010528.3  TPA: putative amidase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010528.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VSM2, P22580
    UniProtKB/TrEMBL
    B3LG47, C8Z5F3, N1P6N5
    Conserved Domains (1) summary
    pfam01425
    Location:79 → 539
    Amidase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P22580.2

Gene LinkOut

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