U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PMP3 Pmp3p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851869, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
PMP3
Official Full Name
Pmp3p
Primary source
SGD:S000002684
Locus tag
YDR276C
See related
AllianceGenome:SGD:S000002684; FungiDB:YDR276C; VEuPathDB:YDR276C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
SNA1
Summary
Enables phospholipid binding activity and sphingolipid binding activity. Involved in monoatomic cation transport and regulation of membrane potential. Located in plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See PMP3 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1013476..1013643, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene triglyceride-associated lipolysis regulator TLD1 Neighboring gene Mth1p Neighboring gene tRNA-Glu

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Phylogenetic and functional analysis of Arabidopsis RCI2 genes. Medina J, et al. J Exp Bot, 2007. PMID 18182435
  2. The low-temperature- and salt-induced RCI2A gene of Arabidopsis complements the sodium sensitivity caused by a deletion of the homologous yeast gene SNA1. Nylander M, et al. Plant Mol Biol, 2001 Feb. PMID 11292079
  3. Overexpression of PDR16 Confers Amphotericin B Resistance in a PMP3-Dependent Manner in Yeast Saccharomyces cerevisiae. Kalra S, et al. Microb Drug Resist, 2024 Jul. PMID 38727600
  4. Molecular characterization of a cold-induced plasma membrane protein gene from wheat. Koike M, et al. Mol Genet Genomics, 2005 Dec. PMID 16184390
  5. Functional responses between PMP3 small membrane proteins and membrane potential. Kwok ACM, et al. Environ Microbiol, 2020 Aug. PMID 32307863

See all (67) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables phosphatidic acid binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphatidylinositol-3,5-bisphosphate binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphatidylinositol-3-phosphate binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables sphingolipid binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in monoatomic cation transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of membrane potential IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Pmp3p
NP_010562.1
  • Small plasma membrane protein; confers resistance to amphotericin B and is a potential target of this common antifungal drug; related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature; not essential for viability; deletion causes hyperpolarization of the plasma membrane potential

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1013476..1013643 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180584.1 → NP_010562.1  TPA: Pmp3p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010562.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VSQ7, P87284
    UniProtKB/TrEMBL
    A6ZYM6, B3LG17, C7GS94, C8Z5I9, G2WB16, N1P712
    Conserved Domains (1) summary
    pfam01679
    Location:5 → 53
    Pmp3; Proteolipid membrane potential modulator
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P87284.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools