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CNM1 Cnm1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852356, updated on 9-Dec-2024

Summary

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Official Symbol
CNM1
Official Full Name
Cnm1p
Primary source
SGD:S000000267
Locus tag
YBR063C
See related
AllianceGenome:SGD:S000000267; FungiDB:YBR063C; VEuPathDB:YBR063C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in organelle localization by membrane tethering. Is active in mitochondrial outer membrane; nuclear envelope; and organelle membrane contact site. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See CNM1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (366970..368184, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene tRNA methyltransferase TRM7 Neighboring gene uncharacterized protein Neighboring gene Ecm2p Neighboring gene Nrg2p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cnm1 mediates nucleus-mitochondria contact site formation in response to phospholipid levels. Eisenberg-Bord M, et al. J Cell Biol, 2021 Nov 1. PMID 34694322, Free PMC Article
  2. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549
  3. Complete DNA sequence of yeast chromosome II. Feldmann H, et al. EMBO J, 1994 Dec 15. PMID 7813418, Free PMC Article
  4. A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A. Ciftci-Yilmaz S, et al. Genetics, 2018 Sep. PMID 30012561, Free PMC Article
  5. Association of yeast Upf1p with direct substrates of the NMD pathway. Johansson MJ, et al. Proc Natl Acad Sci U S A, 2007 Dec 26. PMID 18087042, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in organelle localization by membrane tethering IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial outer membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nuclear envelope IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in organelle membrane contact site IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Cnm1p
NP_009619.1
  • Molecular tether on nuclear membrane; mediates contact by interacting with Tom70p on mitochondria; protein abundance is regulated by phosphatidylcholine, enabling coupling of phospholipid homeostasis with contact extent

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    366970..368184 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178411.1 → NP_009619.1  TPA: Cnm1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009619.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VQ63, P38083
    UniProtKB/TrEMBL
    G2W969, N1P6I2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38083.1

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