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YMC2 organic acid transporter [ Saccharomyces cerevisiae S288C ]

Gene ID: 852401, updated on 9-Dec-2024

Summary

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Official Symbol
YMC2
Official Full Name
organic acid transporter
Primary source
SGD:S000000308
Locus tag
YBR104W
See related
AllianceGenome:SGD:S000000308; FungiDB:YBR104W; VEuPathDB:YBR104W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables organic acid transmembrane transporter activity. Involved in mitochondrial transport and transmembrane transport. Located in mitochondrion. Orthologous to several human genes including SLC25A29 (solute carrier family 25 member 29). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See YMC2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (449667..450656)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene exocyst subunit EXO84 Neighboring gene Sif2p Neighboring gene glucose-induced degradation complex subunit VID24 Neighboring gene Snd3p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular identification and functional characterization of a novel glutamate transporter in yeast and plant mitochondria. Porcelli V, et al. Biochim Biophys Acta Bioenerg, 2018 Nov. PMID 30297026
  2. Mitochondrial transporters involved in oleic acid utilization and glutamate metabolism in yeast. Trotter PJ, et al. Arch Biochem Biophys, 2005 Oct 1. PMID 16140254
  3. Phylogenetic classification of the mitochondrial carrier family of Saccharomyces cerevisiae. el Moualij B, et al. Yeast, 1997 May. PMID 9178508
  4. Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation. Sanchez A, et al. Proc Natl Acad Sci U S A, 2020 Dec 1. PMID 33199619, Free PMC Article
  5. Defining the specificity of cotranslationally acting chaperones by systematic analysis of mRNAs associated with ribosome-nascent chain complexes. del Alamo M, et al. PLoS Biol, 2011 Jul. PMID 21765803, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables glycine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables organic acid transmembrane transporter activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycine transport IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial L-ornithine transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in transmembrane transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
organic acid transporter
NP_009662.3
  • Putative mitochondrial inner membrane transporter; proposed role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; YMC2 has a paralog, YMC1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    449667..450656
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178452.3 → NP_009662.3  TPA: organic acid transporter [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009662.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VQA3, P38087
    UniProtKB/TrEMBL
    B3LN49, B5VE67, C7GUK2, D3UEJ7, G2W9A9, N1P8E7
    Conserved Domains (1) summary
    pfam00153
    Location:235 → 328
    Mito_carr; Mitochondrial carrier protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38087.1

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