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SCM4 Scm4p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852940, updated on 9-Dec-2024

Summary

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Official Symbol
SCM4
Official Full Name
Scm4p
Primary source
SGD:S000003281
Locus tag
YGR049W
See related
AllianceGenome:SGD:S000003281; FungiDB:YGR049W; VEuPathDB:YGR049W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to be involved in autophagy of mitochondrion and macroautophagy. Located in mitochondrial outer membrane. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See SCM4 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (591314..591877)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene transcription factor TFIIIC subunit TFC4 Neighboring gene polyubiquitin-binding protein UFD1 Neighboring gene uncharacterized protein Neighboring gene protein kinase FMP48

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SCM4, a gene that suppresses mutant cdc4 function in budding yeast. Smith SA, et al. Mol Gen Genet, 1992 Nov. PMID 1465103
  2. The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins. Becker T, et al. J Cell Biol, 2011 Aug 8. PMID 21825073, Free PMC Article
  3. Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale. Morgenstern M, et al. Cell Rep, 2017 Jun 27. PMID 28658629, Free PMC Article
  4. Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Zahedi RP, et al. Mol Biol Cell, 2006 Mar. PMID 16407407, Free PMC Article
  5. MitoStores: chaperone-controlled protein granules store mitochondrial precursors in the cytosol. Krämer L, et al. EMBO J, 2023 Apr 3. PMID 36704946, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in autophagy of mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in biological_process ND
No biological Data available
more info
  
involved_in macroautophagy IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial outer membrane HDA PubMed 
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
Scm4p
NP_011563.1
  • Mitochondrial outer membrane hypothetical protein; predicted to have 4 transmembrane segments; import is mediated by Tom70p and Mim1p; interacts genetically with a cdc4 mutation; SCM4 has a paralog, ATG33, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    591314..591877
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181178.1 → NP_011563.1  TPA: Scm4p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011563.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VUI6, P32564, Q45U35
    UniProtKB/TrEMBL
    A6ZV36, B3LIH2, C7GXN4, C8Z8U4, G2WED8, N1P3H4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32564.1

Gene LinkOut

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