U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

EFG1 Efg1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853188, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
EFG1
Official Full Name
Efg1p
Primary source
SGD:S000007608
Locus tag
YGR271C-A
See related
AllianceGenome:SGD:S000007608; FungiDB:YGR271C-A; VEuPathDB:YGR271C-A
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YGR272C
Summary
Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); nuclear RNA surveillance; and re-entry into mitotic cell cycle after pheromone arrest. Located in nucleolus. [provided by Alliance of Genome Resources, Dec 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See EFG1 in Genome Data Viewer
Location:
chromosome: VII
Exon count:
1
Sequence:
Chromosome: VII; NC_001139.9 (1037800..1038501, complement)

Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Yta7p Neighboring gene putative RNA helicase Neighboring gene uncharacterized protein Neighboring gene histone acetyltransferase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001139.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Systematic screening of polyphosphate (poly P) levels in yeast mutant cells reveals strong interdependence with primary metabolism. Freimoser FM, et al. Genome Biol, 2006. PMID 17107617, Free PMC Article
  2. Hypoxic adaptation by Efg1 regulates biofilm formation by Candida albicans. Stichternoth C, et al. Appl Environ Microbiol, 2009 Jun. PMID 19346360, Free PMC Article
  3. Dynamical remodeling of the transcriptome during short-term anaerobiosis in Saccharomyces cerevisiae: differential response and role of Msn2 and/or Msn4 and other factors in galactose and glucose media. Lai LC, et al. Mol Cell Biol, 2005 May. PMID 15870279, Free PMC Article
  4. Genetic interactions of yeast NEP1 (EMG1), encoding an essential factor in ribosome biogenesis. Schilling V, et al. Yeast, 2012 May. PMID 22588997
  5. Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae. Kastenmayer JP, et al. Genome Res, 2006 Mar. PMID 16510898, Free PMC Article

See all (47) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The Efg1-Bud22 dimer associates with the U14 snoRNP contacting the 5' rRNA domain of an early 90S pre-ribosomal particle.
    Title: The Efg1-Bud22 dimer associates with the U14 snoRNP contacting the 5' rRNA domain of an early 90S pre-ribosomal particle.
  2. Efg1 is a novel, nucleolar ribosome biogenesis factor in Saccharomyces cerevisiae that is directly linked to the surveillance of pre-40S particles.
    Title: Turnover of aberrant pre-40S pre-ribosomal particles is initiated by a novel endonucleolytic decay pathway.
  3. During hypoxia, Efg1 rapidly induced expression of all major classes of genes known to be associated with normoxic biofilm formation.
    Title: Hypoxic adaptation by Efg1 regulates biofilm formation by Candida albicans.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in nuclear RNA surveillance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in re-entry into mitotic cell cycle after pheromone arrest IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleolus HDA PubMed 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Efg1p
NP_076891.4
  • Ribosome biogenesis factor required for maturation of 18S rRNA; null mutant is sensitive to hydroxyurea and is delayed in recovering from alpha-factor arrest; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001139.9 Reference assembly

    Range
    1037800..1038501 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184474.3 → NP_076891.4  TPA: Efg1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_076891.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZUS8, D6VV49, P53328, Q3E705
    UniProtKB/TrEMBL
    B3LHX2, B5VJL4, G2WEZ5, N1P9Z6
    Conserved Domains (1) summary
    pfam10153
    Location:29 → 141
    Efg1; rRNA-processing protein Efg1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3E705.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools