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ATG36 Atg36p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853254, updated on 9-Dec-2024

Summary

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Official Symbol
ATG36
Official Full Name
Atg36p
Primary source
SGD:S000003721
Locus tag
YJL185C
See related
AllianceGenome:SGD:S000003721; FungiDB:YJL185C; VEuPathDB:YJL185C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in mitophagy and pexophagy. Located in peroxisome. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ATG36 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (82095..82976, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene tyrosine protein kinase SWE1 Neighboring gene alpha-1,2-mannosyltransferase MNN5 Neighboring gene chromatin DNA-binding EKC/KEOPS complex subunit GON7 Neighboring gene alpha-1,6-mannosyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Peroxisomal PTS1-Import Defect of PEX1- Deficient Cells Is Independent of Pexophagy in Saccharomyces cerevisiae. Mastalski T, et al. Int J Mol Sci, 2020 Jan 29. PMID 32013259, Free PMC Article
  2. Production of the Fragrance Geraniol in Peroxisomes of a Product-Tolerant Baker's Yeast. Gerke J, et al. Front Bioeng Biotechnol, 2020. PMID 33102464, Free PMC Article
  3. Pex3 confines pexophagy receptor activity of Atg36 to peroxisomes by regulating Hrr25-mediated phosphorylation and proteasomal degradation. Meguro S, et al. J Biol Chem, 2020 Nov 27. PMID 32958557, Free PMC Article
  4. The YJL185C, YLR376C and YJR129C genes of Saccharomyces cerevisiae are probably involved in regulation of the glyoxylate cycle. Boniewska-Bernacka E, et al. Acta Biochim Pol, 2006. PMID 17146497
  5. Vac8 determines phagophore assembly site vacuolar localization during nitrogen starvation-induced autophagy. Gatica D, et al. Autophagy, 2021 Jul. PMID 32508216, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Pex3 confines pexophagy receptor activity of Atg36 to peroxisomes by regulating Hrr25-mediated phosphorylation and proteasomal degradation.
    Title: Pex3 confines pexophagy receptor activity of Atg36 to peroxisomes by regulating Hrr25-mediated phosphorylation and proteasomal degradation.
  2. It was concluded that Pex3 recruits the pexophagy receptor Atg36. This reinforces the pivotal role played by Pex3 in coordinating the size of the peroxisome pool, and establishes its role in pexophagy in S. cerevisiae.
    Title: Pex3-anchored Atg36 tags peroxisomes for degradation in Saccharomyces cerevisiae.
  3. the contribution of the ER24 gene product Ylr376Cp and of the two suppressor gene products Yjl185Cp and Yjr129Cp to a complex regulation of the glyoxylate cycle in yea
    Title: The YJL185C, YLR376C and YJR129C genes of Saccharomyces cerevisiae are probably involved in regulation of the glyoxylate cycle.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in autophagy IEA
Inferred from Electronic Annotation
more info
  
involved_in mitophagy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pexophagy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pexophagy IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in peroxisome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Atg36p
NP_012350.1
  • Pex3p interacting protein, required for pexophagy; interacts with Atg8p and Atg11p; mRNA is weakly cell cycle regulated, peaking in G2 phase; YJL185C is a non-essential gene

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    82095..82976 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181618.1 → NP_012350.1  TPA: Atg36p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012350.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VW05, P46983
    UniProtKB/TrEMBL
    A6ZQF0, B3LPU1, N1P8Y5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P46983.1

Gene LinkOut

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