U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

metallo-dependent hydrolase superfamily protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 853375, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Full Name
metallo-dependent hydrolase superfamily protein
Primary source
SGD:S000003606
Locus tag
YJL070C
See related
AllianceGenome:SGD:S000003606; FungiDB:YJL070C; VEuPathDB:YJL070C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Located in mitochondrion. [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (307971..310637, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene DNA replication protein PSF2 Neighboring gene acetyl-CoA:L-glutamate N-acetyltransferase Neighboring gene Utp18p Neighboring gene S-formylglutathione hydrolase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Phenotypic consequences of purine nucleotide imbalance in Saccharomyces cerevisiae. Saint-Marc C, et al. Genetics, 2009 Oct. PMID 19635936, Free PMC Article
  2. Disruption of six ORFs on Saccharomyces cerevisiae chromosome X: the YJL069c gene of unknown function is essential to cell viability. Vandenbol M, et al. Yeast, 1999 Sep 30. PMID 10509023
  3. Exposing the fitness contribution of duplicated genes. DeLuna A, et al. Nat Genet, 2008 May. PMID 18408719
  4. Mapping the functional yeast ABC transporter interactome. Snider J, et al. Nat Chem Biol, 2013 Sep. PMID 23831759, Free PMC Article
  5. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that verexpression of YJL070c instead mimics a loss of AMPD function.
    Title: Phenotypic consequences of purine nucleotide imbalance in Saccharomyces cerevisiae.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
metallo-dependent hydrolase superfamily protein
NP_012465.3
  • Putative metallo-dependent hydrolase superfamily protein; similar to AMP deaminases but lacks key catalytic residues and does not rescue purine nucleotide metabolic defect of quadruple aah1 ade8 amd1 his1 mutant; may regulate purine nucleotide homeostasis as overexpression in an AMD1 strain grown in adenine results in greatly reduced GDP and GTP intracellular levels; not an essential gene; YJL070C has a paralog, YBR284W, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    307971..310637 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181503.3 → NP_012465.3  TPA: metallo-dependent hydrolase superfamily protein [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012465.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VWB3, P40361
    UniProtKB/TrEMBL
    A6ZPQ3, B3LQ41, C7GR43, C8ZB90, N1P1A2
    Conserved Domains (1) summary
    COG1816
    Location:405 → 832
    Add; Adenosine deaminase [Nucleotide transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40361.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.