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PET191 Pet191p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853491, updated on 9-Dec-2024

Summary

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Official Symbol
PET191
Official Full Name
Pet191p
Primary source
SGD:S000003795
Locus tag
YJR034W
See related
AllianceGenome:SGD:S000003795; FungiDB:YJR034W; VEuPathDB:YJR034W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in mitochondrial cytochrome c oxidase assembly. Located in mitochondrial inner membrane and mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 9. Orthologous to human COA5 (cytochrome c oxidase assembly factor 5). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See PET191 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (496683..497009)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase CPR7 Neighboring gene Rav1p Neighboring gene DNA-dependent ATPase RAD26 Neighboring gene putative E3 ubiquitin-protein ligase HUL4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Optimization of ethanol production from starch by an amylolytic nuclear petite Saccharomyces cerevisiae strain. Toksoy Oner E. Yeast, 2006 Sep. PMID 17001624
  2. Flux balance analysis of a genome-scale yeast model constrained by exometabolomic data allows metabolic system identification of genetically different strains. Cakir T, et al. Biotechnol Prog, 2007 Mar-Apr. PMID 17373823
  3. Pet191 is a cytochrome c oxidase assembly factor in Saccharomyces cerevisiae. Khalimonchuk O, et al. Eukaryot Cell, 2008 Aug. PMID 18503002, Free PMC Article
  4. Sequence and chromosomal localization of two PET genes required for cytochrome c oxidase assembly in Saccharomyces cerevisiae. McEwen JE, et al. Curr Genet, 1993 Jan. PMID 8381337
  5. Quantitative analysis of yeast gene function using competition experiments in continuous culture. Baganz F, et al. Yeast, 1998 Nov. PMID 9848233

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial cytochrome c oxidase assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial cytochrome c oxidase assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrial intermembrane space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrial intermembrane space IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Pet191p
NP_012568.1
  • Protein required for assembly of cytochrome c oxidase; exists as an oligomer; described as both an integral mitochondrial inner membrane protein facing the intermembrane space (IMS) and as a soluble IMS protein; contains a twin Cx9C motif; imported into the IMS via the MIA import machinery

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    496683..497009
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181692.1 → NP_012568.1  TPA: Pet191p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012568.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VWK7, Q02772
    UniProtKB/TrEMBL
    A6ZPZ5, B3LQC5, C7GKY6, C8ZBI5, G2WH40, N1P1I7
    Conserved Domains (1) summary
    pfam10203
    Location:4 → 70
    Pet191_N; Cytochrome c oxidase assembly protein PET191
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q02772.1

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