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STR2 cystathionine gamma-synthase [ Saccharomyces cerevisiae S288C ]

Gene ID: 853594, updated on 3-Nov-2024

Summary

Official Symbol
STR2
Official Full Name
cystathionine gamma-synthase
Primary source
SGD:S000003891
Locus tag
YJR130C
See related
AllianceGenome:SGD:S000003891; FungiDB:YJR130C; VEuPathDB:YJR130C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables cystathionine gamma-synthase activity. Involved in transsulfuration. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See STR2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (665218..667137, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein-lysine N-methyltransferase Neighboring gene mannosyl-oligosaccharide 1,2-alpha-mannosidase Neighboring gene Nmd5p

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables cystathionine gamma-synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables cystathionine gamma-synthase activity IEA
Inferred from Electronic Annotation
more info
 
enables cystathionine gamma-synthase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in methionine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in sulfur compound metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in transsulfuration IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in transsulfuration IEA
Inferred from Electronic Annotation
more info
 
involved_in transsulfuration IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cystathionine gamma-synthase
NP_012664.1
  • Cystathionine gamma-synthase, converts cysteine into cystathionine; STR2 has a paralog, YML082W, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    665218..667137 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181788.1NP_012664.1  TPA: cystathionine gamma-synthase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012664.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VWU8, P47164
    UniProtKB/TrEMBL
    A6ZQ85, B3LQL2, C7GM83, C8ZBS8, N1P8X1
    Conserved Domains (1) summary
    COG0626
    Location:203637
    MetC; Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]