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uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 853607, updated on 9-Dec-2024

Summary

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Official Full Name
uncharacterized protein
Primary source
SGD:S000003903
Locus tag
YJR142W
See related
AllianceGenome:SGD:S000003903; FungiDB:YJR142W; VEuPathDB:YJR142W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables 8-oxo-dGDP phosphatase activity. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (697141..698169)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Hir3p Neighboring gene putative polyadenylation protein Neighboring gene dolichyl-phosphate-mannose-protein mannosyltransferase Neighboring gene Mgm101p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A cross-kingdom Nudix enzyme that pre-empts damage in thiamin metabolism. Goyer A, et al. Biochem J, 2013 Sep 15. PMID 23834287
  2. Multiple Nudix family proteins possess mRNA decapping activity. Song MG, et al. RNA, 2013 Mar. PMID 23353937, Free PMC Article
  3. Chromatin-associated genes protect the yeast genome from Ty1 insertional mutagenesis. Nyswaner KM, et al. Genetics, 2008 Jan. PMID 18202368, Free PMC Article
  4. Substrate specificity analysis of protein kinase complex Dbf2-Mob1 by peptide library and proteome array screening. Mah AS, et al. BMC Biochem, 2005 Oct 21. PMID 16242037, Free PMC Article
  5. Dissection of a complex phenotype by functional genomics reveals roles for the yeast cyclin-dependent protein kinase Pho85 in stress adaptation and cell integrity. Huang D, et al. Mol Cell Biol, 2002 Jul. PMID 12077337, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables 8-oxo-dGDP phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 8-oxo-dGDP phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_012676.3
  • 8-oxo-dGTP diphosphatase of the Nudix hydrolase family; converts diphosphates of damaged forms of thiamin to monophosphates; GST fusion protein is a Dbf2p-Mob1p phosphorylation target in a proteome chip analysis; synthetic lethal with PH085 deletion; plays a role in restricting Ty1 transposition

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    697141..698169
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181800.3 → NP_012676.3  TPA: uncharacterized protein YJR142W [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012676.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VWW1, P47173
    UniProtKB/TrEMBL
    A6ZQ98, C7GM71, C8ZBU2, N1P0B7
    Conserved Domains (2) summary
    cd03676
    Location:125 → 315
    Nudix_hydrolase_3; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belong to this superfamily requires a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...
    pfam15916
    Location:80 → 153
    DUF4743; Domain of unknown function (DUF4743)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P47173.1

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