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FAT3 Fat3p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853648, updated on 4-Jan-2025

Summary

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Official Symbol
FAT3
Official Full Name
Fat3p
Primary source
SGD:S000001670
Locus tag
YKL187C
See related
AllianceGenome:SGD:S000001670; FungiDB:YKL187C; VEuPathDB:YKL187C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in long-chain fatty acid transport. Located in cell periphery and mitochondrion. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See FAT3 in Genome Data Viewer
Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (89284..91536, complement)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Hym1p Neighboring gene ATP-binding cassette long-chain fatty acid transporter PXA2 Neighboring gene Mtr2p Neighboring gene DNA-binding transcription repressor ASH1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001143.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Global analysis of condition-specific subcellular protein distribution and abundance. Jung S, et al. Mol Cell Proteomics, 2013 May. PMID 23349476, Free PMC Article
  2. Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Reinders J, et al. Mol Cell Proteomics, 2007 Nov. PMID 17761666
  3. Complete DNA sequence of yeast chromosome XI. Dujon B, et al. Nature, 1994 Jun 2. PMID 8196765
  4. Exploring the yeast acetylome using functional genomics. Kaluarachchi Duffy S, et al. Cell, 2012 May 11. PMID 22579291, Free PMC Article
  5. Essential Function of Mec1, the Budding Yeast ATM/ATR Checkpoint-Response Kinase, in Protein Homeostasis. Corcoles-Saez I, et al. Dev Cell, 2018 Aug 20. PMID 30130531

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in fungal-type cell wall organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in long-chain fatty acid transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cell cortex of cell tip IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cell periphery HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Fat3p
NP_012734.1
  • Protein required for fatty acid uptake; protein abundance increases in cortical patches in response to oleate exposure; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; FAT3 has a paralog, YLR413W, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    89284..91536 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179753.1 → NP_012734.1  TPA: Fat3p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012734.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VX13, P34231
    UniProtKB/TrEMBL
    B5VLX5, C8ZBY9, N1P0M4
    Conserved Domains (1) summary
    cl02193
    Location:210 → 362
    VirB5_like; VirB5 protein family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34231.1

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