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DGR2 Dgr2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853738, updated on 9-Dec-2024

Summary

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Official Symbol
DGR2
Official Full Name
Dgr2p
Primary source
SGD:S000001604
Locus tag
YKL121W
See related
AllianceGenome:SGD:S000001604; FungiDB:YKL121W; VEuPathDB:YKL121W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Orthologous to human WDR44 (WD repeat domain 44). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See DGR2 in Genome Data Viewer
Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (214142..216700)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Ssh4p Neighboring gene signal recognition particle subunit SRP21 Neighboring gene Oac1p Neighboring gene Vph2p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001143.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence of a segment of yeast chromosome XI identifies a new mitochondrial carrier, a new member of the G protein family, and a protein with the PAAKK motif of the H1 histones. Colleaux L, et al. Yeast, 1992 Apr. PMID 1514329
  2. TORC2-Dependent Ypk1-Mediated Phosphorylation of Lam2/Ltc4 Disrupts Its Association with the β-Propeller Protein Laf1 at Endoplasmic Reticulum-Plasma Membrane Contact Sites in the Yeast Saccharomyces cerevisiae. Topolska M, et al. Biomolecules, 2020 Nov 25. PMID 33255682, Free PMC Article
  3. Sterol transporters at membrane contact sites regulate TORC1 and TORC2 signaling. Murley A, et al. J Cell Biol, 2017 Sep 4. PMID 28774891, Free PMC Article
  4. Comprehensive and quantitative analysis of yeast deletion mutants defective in apical and isotropic bud growth. Watanabe M, et al. Curr Genet, 2009 Aug. PMID 19466415
  5. A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth. Ralser M, et al. Proc Natl Acad Sci U S A, 2008 Nov 18. PMID 19004802, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
Dgr2p
NP_012801.1
  • hypothetical protein; null mutant is resistant to 2-deoxy-D-glucose and displays abnormally elongated buds; DGR2 has a paralog, YMR102C, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    214142..216700
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179687.1 → NP_012801.1  TPA: Dgr2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012801.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VXG9, P32330
    UniProtKB/TrEMBL
    B3LQX7, N1P166
    Conserved Domains (2) summary
    sd00039
    Location:176 → 238
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:173 → 506
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32330.1

Gene LinkOut

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