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ENB1 Enb1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854007, updated on 4-Jan-2025

Summary

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Official Symbol
ENB1
Official Full Name
Enb1p
Primary source
SGD:S000005518
Locus tag
YOL158C
See related
AllianceGenome:SGD:S000005518; FungiDB:YOL158C; VEuPathDB:YOL158C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
ARN4
Summary
Enables ferric-enterobactin transmembrane transporter activity. Involved in ferric-enterobactin import into cell. Located in cellular bud membrane. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See ENB1 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (19491..21311, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Css3p Neighboring gene oligo-1,6-glucosidase IMA2 Neighboring gene hexose transporter HXT11

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A gene of the major facilitator superfamily encodes a transporter for enterobactin (Enb1p) in Saccharomyces cerevisiae. Heymann P, et al. Biometals, 2000 Mar. PMID 10831226
  2. Relationship between chloroquine toxicity and iron acquisition in Saccharomyces cerevisiae. Emerson LR, et al. Antimicrob Agents Chemother, 2002 Mar. PMID 11850263, Free PMC Article
  3. Linking the dynamics of chromatin occupancy and transcription with predictive models. Tran TQ, et al. Genome Res, 2021 Jun. PMID 33893157, Free PMC Article
  4. Trafficking of siderophore transporters in Saccharomyces cerevisiae and intracellular fate of ferrioxamine B conjugates. Froissard M, et al. Traffic, 2007 Nov. PMID 17714436, Free PMC Article
  5. Cellular iron utilization is regulated by putative siderophore transporter FgSit1 not by free iron transporter in Fusarium graminearum. Park YS, et al. Biochem Biophys Res Commun, 2006 Jul 14. PMID 16750173

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ferric-enterobactin transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables siderophore-iron transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ferric-enterobactin import into cell IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular iron ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in siderophore transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in cellular bud membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endosome IEA
Inferred from Electronic Annotation
more info
  
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
  
located_in fungal-type vacuole HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in vacuolar membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Enb1p
NP_014484.1
  • Ferric enterobactin transmembrane transporter; expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    19491..21311 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183411.1 → NP_014484.1  TPA: Enb1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014484.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W1R2, Q08299
    UniProtKB/TrEMBL
    B5VR99, N1NXM6
    Conserved Domains (1) summary
    cd17322
    Location:63 → 574
    MFS_ARN_like; Yeast ARN family of Siderophore iron transporters and similar proteins of the Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08299.1

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