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HMS1 Hms1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854197, updated on 9-Dec-2024

Summary

Official Symbol
HMS1
Official Full Name
Hms1p
Primary source
SGD:S000005558
Locus tag
YOR032C
See related
AllianceGenome:SGD:S000005558; FungiDB:YOR032C; VEuPathDB:YOR032C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable DNA-binding transcription activator activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in pseudohyphal growth. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See HMS1 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (389771..391075, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Dfg16p Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene Rad2 family nuclease EXO1

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in pseudohyphal growth IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Hms1p
NP_014675.1
  • bHLH protein with similarity to myc-family transcription factors; overexpression confers hyperfilamentous growth and suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    389771..391075 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183451.1NP_014675.1  TPA: Hms1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014675.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W297, Q12398
    UniProtKB/TrEMBL
    G2WMR2, N1P2Y6
    Conserved Domains (1) summary
    cd11399
    Location:265363
    bHLHzip_scHMS1_like; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in Saccharomyces cerevisiae transcription factor HMS1 and similar proteins