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PIN2 Pin2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854271, updated on 9-Dec-2024

Summary

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Official Symbol
PIN2
Official Full Name
Pin2p
Primary source
SGD:S000005630
Locus tag
YOR104W
See related
AllianceGenome:SGD:S000005630; FungiDB:YOR104W; VEuPathDB:YOR104W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Located in cellular bud neck and plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See PIN2 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (517642..518490)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Ras family GTPase RAS1 Neighboring gene dolichyl-diphosphooligosaccharide-protein glycotransferase Neighboring gene uncharacterized protein Neighboring gene SNAP receptor VAM3 Neighboring gene GTPase-activating protein RGS2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Prions affect the appearance of other prions: the story of [PIN(+)]. Derkatch IL, et al. Cell, 2001 Jul 27. PMID 11511345
  2. A bipolar functionality of Q/N-rich proteins: Lsm4 amyloid causes clearance of yeast prions. Oishi K, et al. Microbiologyopen, 2013 Jun. PMID 23512891, Free PMC Article
  3. The Functional Specialization of Exomer as a Cargo Adaptor During the Evolution of Fungi. Anton C, et al. Genetics, 2018 Apr. PMID 29437703, Free PMC Article
  4. The prion-like domain in the exomer-dependent cargo Pin2 serves as a trans-Golgi retention motif. Ritz AM, et al. Cell Rep, 2014 Apr 10. PMID 24656818
  5. Dynamic assembly of the exomer secretory vesicle cargo adaptor subunits. Huranova M, et al. EMBO Rep, 2016 Feb. PMID 26742961, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular bud neck IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cellular bud neck IDA
Inferred from Direct Assay
more info
 PubMed 
located_in fungal-type vacuole membrane HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Pin2p
NP_014747.1
  • Exomer-dependent cargo protein; induces appearance of [PIN+] prion when overproduced; prion-like domain serves as a retention signal in the trans-Golgi network; predicted to be palmitoylated

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    517642..518490
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183523.1 → NP_014747.1  TPA: Pin2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014747.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W2G4, Q12057
    UniProtKB/TrEMBL
    A6ZNV3, B3LJE9, B5VRZ6, C7GMN1, G2WMY0, N1P338
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12057.1

Gene LinkOut

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