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CIM1 mitochondrial HMG-box protein CIM1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854281, updated on 4-Jan-2025

Summary

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Official Symbol
CIM1
Official Full Name
mitochondrial HMG-box protein CIM1
Primary source
SGD:S000005640
Locus tag
YOR114W
See related
AllianceGenome:SGD:S000005640; FungiDB:YOR114W; VEuPathDB:YOR114W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
DPI34
Summary
Acts upstream of or within mitochondrial genome maintenance. Is active in mitochondrial matrix. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See CIM1 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (537570..538454)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Cex1p Neighboring gene Azf1p Neighboring gene Trs33p Neighboring gene DNA-directed RNA polymerase III core subunit RPO31

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Two mitochondrial HMG-box proteins, Cim1 and Abf2, antagonistically regulate mtDNA copy number in Saccharomyces cerevisiae. Schrott S, et al. Nucleic Acids Res, 2023 Nov 27. PMID 37850632, Free PMC Article
  2. Polymorphisms in multiple genes contribute to the spontaneous mitochondrial genome instability of Saccharomyces cerevisiae S288C strains. Dimitrov LN, et al. Genetics, 2009 Sep. PMID 19581448, Free PMC Article
  3. Two Routes to Genetic Suppression of RNA Trimethylguanosine Cap Deficiency via C-Terminal Truncation of U1 snRNP Subunit Snp1 or Overexpression of RNA Polymerase Subunit Rpo26. Qiu ZR, et al. G3 (Bethesda), 2015 Apr 24. PMID 25911228, Free PMC Article
  4. Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale. Morgenstern M, et al. Cell Rep, 2017 Jun 27. PMID 28658629, Free PMC Article
  5. Yeast Nst1 is a novel component of P-bodies and is a specific suppressor of proteasome base assembly defects. Cheng CL, et al. Mol Biol Cell, 2021 Oct 1. PMID 34347506, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Two mitochondrial HMG-box proteins, Cim1 and Abf2, antagonistically regulate mtDNA copy number in Saccharomyces cerevisiae.
    Title: Two mitochondrial HMG-box proteins, Cim1 and Abf2, antagonistically regulate mtDNA copy number in Saccharomyces cerevisiae.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within mitochondrial genome maintenance IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within mitochondrial genome maintenance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in mitochondrial matrix IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
mitochondrial HMG-box protein CIM1
NP_014757.1
  • Mitochondrial HMG-box protein; limits the copy number of mitochondrial DNA (mtDNA), antagonizing HMG-box containing protein Abf2p, a mtDNA packaging factor; localizes to the mitochondrial matrix; contains two HMG-boxes similar to Abf2p; null mutant is viable

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    537570..538454
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183533.1 → NP_014757.1  TPA: mitochondrial HMG-box protein CIM1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014757.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W2H3, Q12219
    UniProtKB/TrEMBL
    A6ZNW2, C7GMM2, G2WMZ0, N1P345
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12219.1

Gene LinkOut

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