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RPL33B ribosomal 60S subunit protein L33B [ Saccharomyces cerevisiae S288C ]

Gene ID: 854409, updated on 4-Jan-2025

Summary

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Official Symbol
RPL33B
Official Full Name
ribosomal 60S subunit protein L33B
Primary source
SGD:S000005760
Locus tag
YOR234C
See related
AllianceGenome:SGD:S000005760; FungiDB:YOR234C; VEuPathDB:YOR234C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RPL37B
Summary
A structural constituent of ribosome. Involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 5. Orthologous to human RPL35A (ribosomal protein L35a). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See RPL33B in Genome Data Viewer
Location:
chromosome: XV
Exon count:
2
Sequence:
Chromosome: XV; NC_001147.6 (778555..779405, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Mge1p Neighboring gene putative serine/threonine protein kinase KIN4 Neighboring gene Irc13p Neighboring gene ncRNA Neighboring gene dihydrofolate reductase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Saccharomyces cerevisiae ribosomal protein L37 is encoded by duplicate genes that are differentially expressed. Tornow J, et al. Curr Genet, 1994 Jun. PMID 8082197
  2. Introns within ribosomal protein genes regulate the production and function of yeast ribosomes. Parenteau J, et al. Cell, 2011 Oct 14. PMID 22000012
  3. A High-Copy Suppressor Screen Reveals a Broad Role of Prefoldin-like Bud27 in the TOR Signaling Pathway in Saccharomyces cerevisiae. Gutiérrez-Santiago F, et al. Genes (Basel), 2022 Apr 24. PMID 35627133, Free PMC Article
  4. Yeast ribosomal proteins. VIII. Isolation of two proteins and sequence characterization of twenty-four proteins from cytoplasmic ribosomes. Otaka E, et al. Mol Gen Genet, 1984. PMID 18782943
  5. Novel interactions of Saccharomyces cerevisiae type 1 protein phosphatase identified by single-step affinity purification and mass spectrometry. Walsh EP, et al. Biochemistry, 2002 Feb 19. PMID 11841235

See all (74) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cytoplasmic translation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in ribosomal large subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal 60S subunit protein L33B
NP_014877.3
  • Ribosomal 60S subunit protein L33B; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable; homologous to mammalian ribosomal protein L35A, no bacterial homolog; RPL33B has a paralog, RPL33A, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    778555..779405 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183653.3 → NP_014877.3  TPA: ribosomal 60S subunit protein L33B [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014877.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W2T8, P41056
    UniProtKB/TrEMBL
    A6ZP75, C8ZGY8, G2WNA4, N1NVW4
    Conserved Domains (1) summary
    pfam01247
    Location:7 → 100
    Ribosomal_L35Ae; Ribosomal protein L35Ae
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P41056.2

Gene LinkOut

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