U.S. flag

An official website of the United States government

TPO4 Tpo4p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854447, updated on 9-Dec-2024

Summary

Official Symbol
TPO4
Official Full Name
Tpo4p
Primary source
SGD:S000005799
Locus tag
YOR273C
See related
AllianceGenome:SGD:S000005799; FungiDB:YOR273C; VEuPathDB:YOR273C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables spermidine transmembrane transporter activity and spermine transmembrane transporter activity. Involved in spermidine transport and spermine transport. Located in fungal-type vacuole membrane and plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See TPO4 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (834452..836431, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Ytm1p Neighboring gene tRNA dimethylallyltransferase Neighboring gene Rim20p

Interactions

General gene information

Gene Ontology Provided by SGD

Process Evidence Code Pubs
involved_in spermidine transmembrane transport  
involved_in spermidine transport  
involved_in spermidine transport PubMed 
involved_in spermine transmembrane transport  
involved_in spermine transport  
involved_in spermine transport PubMed 
involved_in transmembrane transport  
involved_in transmembrane transport  
Component Evidence Code Pubs
located_in cell periphery PubMed 
located_in fungal-type vacuole membrane PubMed 
located_in membrane  
is_active_in plasma membrane  
located_in plasma membrane PubMed 
located_in plasma membrane  

General protein information

Preferred Names
Tpo4p
NP_014916.1
  • Polyamine transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; recognizes spermine, putrescine, and spermidine; localizes to the plasma membrane

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    834452..836431 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183692.1 → NP_014916.1  TPA: Tpo4p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014916.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W2X3, Q12256
    UniProtKB/TrEMBL
    G2WNE1, N1NXC2
    Conserved Domains (1) summary
    cd17323
    Location:95 → 546
    MFS_Tpo1_MDR_like; Yeast Polyamine transporter 1 (Tpo1) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily
External link. Please review our privacy policy.