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PDR10 ATP-binding cassette multidrug transporter PDR10 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854506, updated on 4-Jan-2025

Summary

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Official Symbol
PDR10
Official Full Name
ATP-binding cassette multidrug transporter PDR10
Primary source
SGD:S000005855
Locus tag
YOR328W
See related
AllianceGenome:SGD:S000005855; FungiDB:YOR328W; VEuPathDB:YOR328W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in replication-born double-strand break repair via sister chromatid exchange. Located in plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See PDR10 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (931803..936497)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene myosin 2 Neighboring gene SNAP receptor SNC2 Neighboring gene Scd5p Neighboring gene DNA-directed DNA polymerase gamma MIP1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Construction of reporter gene assays using CWP and PDR mutant yeasts for enhanced detection of various sex steroids. Ito-Harashima S, et al. Genes Environ, 2020. PMID 32514322, Free PMC Article
  2. The yeast ATP binding cassette (ABC) protein genes PDR10 and PDR15 are novel targets for the Pdr1 and Pdr3 transcriptional regulators. Wolfger H, et al. FEBS Lett, 1997 Dec 1. PMID 9428726
  3. Hypervariable noncoding sequences in Saccharomyces cerevisiae. Fay JC, et al. Genetics, 2005 Aug. PMID 15956668, Free PMC Article
  4. Engineering endogenous ABC transporter with improving ATP supply and membrane flexibility enhances the secretion of β-carotene in Saccharomyces cerevisiae. Bu X, et al. Biotechnol Biofuels, 2020. PMID 33062054, Free PMC Article
  5. ATPase and multidrug transport activities of the overexpressed yeast ABC protein Yor1p. Decottignies A, et al. J Biol Chem, 1998 May 15. PMID 9575223

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in replication-born double-strand break repair via sister chromatid exchange IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in xenobiotic detoxification by transmembrane export across the plasma membrane IEA
Inferred from Electronic Annotation
more info
  
involved_in xenobiotic detoxification by transmembrane export across the plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in fungal-type vacuole HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ATP-binding cassette multidrug transporter PDR10
NP_014973.1
  • ATP-binding cassette (ABC) transporter; multidrug transporter involved in the pleiotropic drug resistance network; regulated by Pdr1p and Pdr3p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    931803..936497
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183748.1 → NP_014973.1  TPA: ATP-binding cassette multidrug transporter PDR10 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014973.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W325, P51533
    UniProtKB/TrEMBL
    B3LJY9, C7GNT6, C8ZH79, N1NX10
    Conserved Domains (1) summary
    TIGR00956
    Location:110 → 1556
    3a01205; Pleiotropic Drug Resistance (PDR) Family protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P51533.1

Gene LinkOut

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