U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CSI1 Csi1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855040, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
CSI1
Official Full Name
Csi1p
Primary source
SGD:S000004627
Locus tag
YMR025W
See related
AllianceGenome:SGD:S000004627; FungiDB:YMR025W; VEuPathDB:YMR025W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in cellular response to pheromone; conjugation with cellular fusion; and protein deneddylation. Part of COP9 signalosome. [provided by Alliance of Genome Resources, Dec 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CSI1 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (323300..324187)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene tRNA-Ala Neighboring gene mitochondrial 54S ribosomal protein YmL3 Neighboring gene ubiquitin-protein ligase peroxin 12 Neighboring gene putative methyltransferase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Chemogenomic study of gemcitabine using Saccharomyces cerevisiae as model cell-molecular insights about chemoresistance. de Sousa Cavalcante L, et al. Braz J Microbiol, 2020 Jun. PMID 31515725, Free PMC Article
  2. Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms. Nestoras K, et al. Genes Dev, 2010 Jun 1. PMID 20516199, Free PMC Article
  3. The COP9 signalosome is involved in the regulation of lipid metabolism and of transition metals uptake in Saccharomyces cerevisiae. Licursi V, et al. FEBS J, 2014 Jan. PMID 24164706
  4. Saccharomyces cerevisiae as a Toolkit for COP9 Signalosome Research. Harshuk-Shabso D, et al. Biomolecules, 2021 Mar 25. PMID 33806190, Free PMC Article
  5. Conservation of the COP9/signalosome in budding yeast. Wee S, et al. BMC Genet, 2002 Aug 20. PMID 12186635, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cellular response to pheromone IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in conjugation with cellular fusion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein deneddylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of COP9 signalosome IDA
Inferred from Direct Assay
more info
 PubMed 
part_of COP9 signalosome IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Csi1p
NP_013738.1
  • Subunit of the Cop9 signalosome; which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling; functional equivalent of canonical Csn6 subunit of the COP9 signalosome

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    323300..324187
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182521.1 → NP_013738.1  TPA: Csi1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013738.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VZJ9, Q04368
    UniProtKB/TrEMBL
    A6ZM87, B3LLS6, B5VPF2, C7GL94, C8ZEN2, N1P5C5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q04368.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools