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EIS1 Eis1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855047, updated on 9-Dec-2024

Summary

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Official Symbol
EIS1
Official Full Name
Eis1p
Primary source
SGD:S000004633
Locus tag
YMR031C
See related
AllianceGenome:SGD:S000004633; FungiDB:YMR031C; VEuPathDB:YMR031C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in eisosome assembly. Located in eisosome. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See EIS1 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (332212..334743, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Far8p Neighboring gene Rsf1p Neighboring gene formin-binding protein HOF1 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Seg1 controls eisosome assembly and shape. Moreira KE, et al. J Cell Biol, 2012 Aug 6. PMID 22869600, Free PMC Article
  2. Plasma membrane microdomains regulate turnover of transport proteins in yeast. Grossmann G, et al. J Cell Biol, 2008 Dec 15. PMID 19064668, Free PMC Article
  3. Fungal BLAST and Model Organism BLASTP Best Hits: new comparison resources at the Saccharomyces Genome Database (SGD). Balakrishnan R, et al. Nucleic Acids Res, 2005 Jan 1. PMID 15608219, Free PMC Article
  4. A role for eisosomes in maintenance of plasma membrane phosphoinositide levels. Fröhlich F, et al. Mol Biol Cell, 2014 Sep 15. PMID 25057013, Free PMC Article
  5. Unifying fluorescence microscopy and mass spectrometry for studying protein complexes in cells. Deng C, et al. Mol Cell Proteomics, 2009 Jun. PMID 19269952, Free PMC Article

See all (61) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in eisosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in eisosome assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in cytoplasm HDA PubMed 
located_in eisosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in eisosome IGI
Inferred from Genetic Interaction
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in plasma membrane HDA PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Eis1p
NP_013744.1
  • Component of the eisosome required for proper eisosome assembly; similar to Uso1p; authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; protein increases in abundance and relocalizes from plasma membrane to cytoplasm upon DNA replication stress; EIS1 has a paralog, YKL050C, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    332212..334743 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182527.1 → NP_013744.1  TPA: Eis1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013744.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B3LLS9, B5VPF9, C7GL88, D6VZK5, Q05050
    UniProtKB/TrEMBL
    N1P068
    Conserved Domains (2) summary
    COG1196
    Location:415 → 736
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam12757
    Location:324 → 442
    Eisosome1; Eisosome protein 1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q05050.1

Gene LinkOut

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