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SEC21 coatomer subunit gamma [ Saccharomyces cerevisiae S288C ]

Gene ID: 855429, updated on 9-Dec-2024

Summary

Official Symbol
SEC21
Official Full Name
coatomer subunit gamma
Primary source
SGD:S000005231
Locus tag
YNL287W
See related
AllianceGenome:SGD:S000005231; FungiDB:YNL287W; VEuPathDB:YNL287W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable structural molecule activity. Involved in endoplasmic reticulum to Golgi vesicle-mediated transport and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Part of COPI vesicle coat. Orthologous to human COPG1 (COPI coat complex subunit gamma 1) and COPG2 (COPI coat complex subunit gamma 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See SEC21 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (91994..94801)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene CCR4-NOT core subunit CAF40 Neighboring gene U2 snRNP complex subunit CUS2 Neighboring gene tRNA-Gly

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in protein secretion IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of COPI vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of COPI vesicle coat IDA
Inferred from Direct Assay
more info
PubMed 
part_of COPI vesicle coat IEA
Inferred from Electronic Annotation
more info
 
located_in COPI-coated vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
coatomer subunit gamma
NP_014112.1
  • Gamma subunit of coatomer; coatomer is a heptameric protein complex that together with Arf1p forms the COPI coat; involved in ER to Golgi transport of selective cargo

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    91994..94801
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183125.1NP_014112.1  TPA: coatomer subunit gamma [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014112.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0Q6, P32074
    UniProtKB/TrEMBL
    A6ZSJ1, B3LPC5, B5VQD0, C7GS50, C8ZGN4, G2WLI0, N1NZV4
    Conserved Domains (3) summary
    COG5240
    Location:1935
    SEC21; Vesicle coat complex COPI, gamma subunit [Intracellular trafficking and secretion]
    sd00044
    Location:416442
    HEAT; HEAT repeat [structural motif]
    sd00043
    Location:298334
    ARM; armadillo repeat [structural motif]