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MRPS12 putative mitochondrial 37S ribosomal protein MRPS12 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855772, updated on 9-Dec-2024

Summary

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Official Symbol
MRPS12
Official Full Name
putative mitochondrial 37S ribosomal protein MRPS12
Primary source
SGD:S000005319
Locus tag
YNR036C
See related
AllianceGenome:SGD:S000005319; FungiDB:YNR036C; VEuPathDB:YNR036C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
uS12m
Summary
A structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial small ribosomal subunit. Used to study dilated cardiomyopathy. Orthologous to human MRPS12 (mitochondrial ribosomal protein S12). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See MRPS12 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (694361..694822, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Ego4p Neighboring gene Arc35p Neighboring gene mitochondrial 37S ribosomal protein RSM19 Neighboring gene putative ATP-dependent RNA helicase DBP6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cross-genomic analysis of the translational systems of various organisms. Fujita K, et al. J Ind Microbiol Biotechnol, 2001 Sep. PMID 11780787
  2. Adaptation, chance, and history in experimental evolution reversals to unicellularity. Rebolleda-Gómez M, et al. Evolution, 2019 Jan. PMID 30520011, Free PMC Article
  3. Mitochondrial Translation Efficiency Controls Cytoplasmic Protein Homeostasis. Suhm T, et al. Cell Metab, 2018 Jun 5. PMID 29754951
  4. Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components. Gan X, et al. Eur J Biochem, 2002 Nov. PMID 12392552
  5. Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Fleischer TC, et al. Genes Dev, 2006 May 15. PMID 16702403, Free PMC Article

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation IC
Inferred by Curator
more info
 PubMed 
involved_in mitochondrial translation ISA
Inferred from Sequence Alignment
more info
 PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of mitochondrial small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of mitochondrial small ribosomal subunit ISA
Inferred from Sequence Alignment
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
is_active_in ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
part_of small ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative mitochondrial 37S ribosomal protein MRPS12
NP_014434.1
  • Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    694361..694822 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183213.1 → NP_014434.1  TPA: putative mitochondrial 37S ribosomal protein MRPS12 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014434.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W1L2, P53732
    UniProtKB/TrEMBL
    A6ZSB1, B3LPK6, C7GLM0, G2WL94, N1NWU4
    Conserved Domains (1) summary
    TIGR00981
    Location:28 → 152
    rpsL_bact; ribosomal protein S12, bacterial/organelle
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53732.1

Gene LinkOut

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