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AGA1 Aga1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855780, updated on 4-Jan-2025

Summary

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Official Symbol
AGA1
Official Full Name
Aga1p
Primary source
SGD:S000005327
Locus tag
YNR044W
See related
AllianceGenome:SGD:S000005327; FungiDB:YNR044W; VEuPathDB:YNR044W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables cell adhesion molecule binding activity. Involved in agglutination involved in conjugation with cellular fusion. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See AGA1 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (703699..705876)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene 4-hydroxybenzoate octaprenyltransferase Neighboring gene diphosphomevalonate decarboxylase MVD1 Neighboring gene Pet494p Neighboring gene RNA methylation protein TRM112

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sexual agglutination in budding yeasts: structure, function, and regulation of adhesion glycoproteins. Lipke PN, et al. Microbiol Rev, 1992 Mar. PMID 1579109, Free PMC Article
  2. The AGA1 product is involved in cell surface attachment of the Saccharomyces cerevisiae cell adhesion glycoprotein a-agglutinin. Roy A, et al. Mol Cell Biol, 1991 Aug. PMID 2072914, Free PMC Article
  3. Establishment of a simple system to analyse the molecular interaction in the agglutination of Saccharomyces cerevisiae. Zou W, et al. Yeast, 2000 Aug. PMID 10923021
  4. Construction of an in vitro trans-sialylation system: surface display of Corynebacterium diphtheriae sialidase on Saccharomyces cerevisiae. Kim S, et al. Appl Microbiol Biotechnol, 2010 Oct. PMID 20711574
  5. Delineation of functional regions within the subunits of the Saccharomyces cerevisiae cell adhesion molecule a-agglutinin. Shen ZM, et al. J Biol Chem, 2001 May 11. PMID 11278672

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables cell adhesion molecule binding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in agglutination involved in conjugation with cellular fusion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
  
involved_in response to pheromone IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in fungal-type cell wall IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Aga1p
NP_014442.1
  • Anchorage subunit of a-agglutinin of a-cells; highly O-glycosylated protein with N-terminal secretion signal and C-terminal signal for addition of GPI anchor to cell wall, linked to adhesion subunit Aga2p via two disulfide bonds; AGA1 has a paralog, FIG2, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    703699..705876
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183221.1 → NP_014442.1  TPA: Aga1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014442.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W1L9, P32323
    UniProtKB/TrEMBL
    C7GLL3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32323.1

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