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GDE1 glycerophosphocholine phosphodiesterase [ Saccharomyces cerevisiae S288C ]

Gene ID: 855994, updated on 9-Dec-2024

Summary

Official Symbol
GDE1
Official Full Name
glycerophosphocholine phosphodiesterase
Primary source
SGD:S000006031
Locus tag
YPL110C
See related
AllianceGenome:SGD:S000006031; FungiDB:YPL110C; VEuPathDB:YPL110C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables glycerophosphocholine phosphodiesterase activity. Involved in glycerophospholipid catabolic process. Located in cytoplasm. Orthologous to human GPCPD1 (glycerophosphocholine phosphodiesterase 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See GDE1 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (341068..344739, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene tRNA-Met Neighboring gene arginase Neighboring gene Cqd1p Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Genomic Sequence:
NC_001148.4

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

General gene information

Gene Ontology Provided by SGD

Component Evidence Code Pubs
located_in cytoplasm PubMed 
located_in cytoplasm  

General protein information

Preferred Names
glycerophosphocholine phosphodiesterase
NP_015215.1
  • Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphosphate, for use as a phosphate source and as a precursor for phosphocholine synthesis; may interact with ribosomes

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    341068..344739 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183924.1 → NP_015215.1  TPA: glycerophosphocholine phosphodiesterase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015215.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W3Q7, Q02979
    UniProtKB/TrEMBL
    B3LKW3, C7GJ64, N1NX43
    Conserved Domains (5) summary
    cd08606
    Location:871 → 1219
    GDPD_YPL110cp_fungi; Glycerophosphodiester phosphodiesterase domain of Saccharomyces cerevisiae YPL110cp and similar proteins
    COG0666
    Location:361 → 594
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    COG5408
    Location:1 → 300
    COG5408; SPX domain-containing protein [Signal transduction mechanisms]
    sd00045
    Location:540 → 569
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:508 → 603
    Ank_2; Ankyrin repeats (3 copies)
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