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YTA6 putative AAA family ATPase YTA6 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856031, updated on 4-Jan-2025

Summary

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Official Symbol
YTA6
Official Full Name
putative AAA family ATPase YTA6
Primary source
SGD:S000005995
Locus tag
YPL074W
See related
AllianceGenome:SGD:S000005995; FungiDB:YPL074W; VEuPathDB:YPL074W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable ATP hydrolysis activity. Involved in positive regulation of translation. Located in cell cortex. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 4. Orthologous to human SPAST (spastin). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See YTA6 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (415763..418027)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol N-acetylglucosaminyltransferase Neighboring gene transcription regulator GCR1 Neighboring gene putative ubiquitin-specific protease UBP16 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ASH1 mRNA localization in three acts. Beach DL, et al. Mol Biol Cell, 2001 Sep. PMID 11553699, Free PMC Article
  2. Identification of a set of yeast genes coding for a novel family of putative ATPases with high similarity to constituents of the 26S protease complex. Schnall R, et al. Yeast, 1994 Sep. PMID 7754704
  3. The evolution of the conserved ATPase domain (CAD): reconstructing the history of an ancient protein module. Swaffield JC, et al. J Mol Evol, 1997 Nov. PMID 9342402
  4. Protein phosphatase type 1 interacts with proteins required for meiosis and other cellular processes in Saccharomyces cerevisiae. Tu J, et al. Mol Cell Biol, 1996 Aug. PMID 8754819, Free PMC Article
  5. Genetic interactions between GLC7, PPZ1 and PPZ2 in saccharomyces cerevisiae. Venturi GM, et al. Genetics, 2000 May. PMID 10790385, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of translation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell cortex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm HDA PubMed 

General protein information

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Preferred Names
putative AAA family ATPase YTA6
NP_015251.1
  • Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family; localized to the cortex of mother cells but not to daughter cells; relocalizes from cytoplasm to plasma membrane foci upon DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    415763..418027
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183888.1 → NP_015251.1  TPA: putative AAA family ATPase YTA6 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015251.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W3U2, P40324, P40328, Q02845, Q05773
    UniProtKB/TrEMBL
    A6ZWH6, B3LKZ6, C7GTY4, N1NVH5
    Conserved Domains (1) summary
    COG0464
    Location:201 → 747
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40328.2

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