MNN9 mannosyltransferase complex subunit MNN9 [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: MNN9
Official Full Name: mannosyltransferase complex subunit MNN9
Primary source: SGD:S000005971
Locus tag: YPL050C
See related: AllianceGenome:SGD:S000005971; FungiDB:YPL050C; VEuPathDB:YPL050C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Contributes to alpha-1,6-mannosyltransferase activity. Involved in protein N-linked glycosylation. Located in cis-Golgi network. Part of mannan polymerase complex. [provided by Alliance of Genome Resources, Jan 2025]
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Chromosome XVI - NC_001148.4 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

This study presents the structure of MNN9 in complex with Guanosine Diphosphate and Mn(2+).
Title: Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis.
These results provide further information on the role of M-Pol I and its subunits Mnn9 and Van1 in mannan biosynthesis.
Title: Expression and purification of recombinant M-Pol I from Saccharomyces cerevisiae with alpha-1,6 mannosylpolymerase activity.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to alpha-1,6-mannosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
contributes_to alpha-1,6-mannosyltransferase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in cell wall mannoprotein biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein N-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein N-linked glycosylation	IDA Inferred from Direct Assay more info	PubMed
involved_in protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in cis-Golgi network	IDA Inferred from Direct Assay more info	PubMed
located_in endoplasmic reticulum	HDA more info	PubMed
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
part_of mannan polymerase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mannan polymerase complex	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info

NP_015275.1

Subunit of Golgi mannosyltransferase complex; this complex mediates elongation of the polysaccharide mannan backbone; forms a separate complex with Van1p that is also involved in backbone elongation; this complex also contains Anp1p, Mnn10p, Mnn11p, and Hoc1p