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CMR3 Cmr3p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856123, updated on 9-Dec-2024

Summary

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Official Symbol
CMR3
Official Full Name
Cmr3p
Primary source
SGD:S000006217
Locus tag
YPR013C
See related
AllianceGenome:SGD:S000006217; FungiDB:YPR013C; VEuPathDB:YPR013C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables DNA binding activity. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1K and osteogenesis imperfecta type 12. Orthologous to human SP6 (Sp6 transcription factor) and SP7 (Sp7 transcription factor). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See CMR3 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (584632..585585, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Mra1p Neighboring gene Mrx21p Neighboring gene uncharacterized protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptome profiling of Saccharomyces cerevisiae mutants lacking C2H2 zinc finger proteins. Mao J, et al. BMC Genomics, 2008. PMID 18366603, Free PMC Article
  2. Massively parallel measurements of molecular interaction kinetics on a microfluidic platform. Geertz M, et al. Proc Natl Acad Sci U S A, 2012 Oct 9. PMID 23012409, Free PMC Article
  3. High-resolution DNA-binding specificity analysis of yeast transcription factors. Zhu C, et al. Genome Res, 2009 Apr. PMID 19158363, Free PMC Article
  4. Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Finch AJ, et al. Genes Dev, 2011 May 1. PMID 21536732, Free PMC Article
  5. Variations of the C2H2 zinc finger motif in the yeast genome and classification of yeast zinc finger proteins. Böhm S, et al. Nucleic Acids Res, 1997 Jun 15. PMID 9171100, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding HDA PubMed 
enables zinc ion binding RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Cmr3p
NP_015338.1
  • Putative zinc finger protein; YPR013C is not an essential gene

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    584632..585585 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184110.1 → NP_015338.1  TPA: Cmr3p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015338.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W424, Q12145
    UniProtKB/TrEMBL
    A6ZWQ7, B3LL73, C7GV38, N1NW03
    Conserved Domains (2) summary
    COG5048
    Location:17 → 316
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00019
    Location:256 → 276
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12145.1

Gene LinkOut

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