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uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 856125, updated on 9-Dec-2024

Summary

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Official Full Name
uncharacterized protein
Primary source
SGD:S000006219
Locus tag
YPR015C
See related
AllianceGenome:SGD:S000006219; FungiDB:YPR015C; VEuPathDB:YPR015C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable zinc ion binding activity. Involved in DNA damage checkpoint signaling. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (590283..591026, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene translation initiation factor 6 Neighboring gene guanine nucleotide exchange factor DSS4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptome profiling of Saccharomyces cerevisiae mutants lacking C2H2 zinc finger proteins. Mao J, et al. BMC Genomics, 2008. PMID 18366603, Free PMC Article
  2. Functional Analysis of Kinases and Transcription Factors in Saccharomyces cerevisiae Using an Integrated Overexpression Library. Youn JY, et al. G3 (Bethesda), 2017 Mar 10. PMID 28122947, Free PMC Article
  3. Mechanisms of cell cycle control revealed by a systematic and quantitative overexpression screen in S. cerevisiae. Niu W, et al. PLoS Genet, 2008 Jul 11. PMID 18617996, Free PMC Article
  4. Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Finch AJ, et al. Genes Dev, 2011 May 1. PMID 21536732, Free PMC Article
  5. Functional analysis with a barcoder yeast gene overexpression system. Douglas AC, et al. G3 (Bethesda), 2012 Oct. PMID 23050238, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage checkpoint signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_015340.1
  • Putative zinc finger transcription factor; binds DNA in sequence-specific manner; overexpression causes a cell cycle delay or arrest

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    590283..591026 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184112.1 → NP_015340.1  TPA: uncharacterized protein YPR015C [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015340.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W425, Q12531, Q6Q5F4
    UniProtKB/TrEMBL
    A6ZWQ8, B3LL76, B5VTH4, C8ZJ39, N1NVJ3
    Conserved Domains (2) summary
    COG5048
    Location:17 → 247
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00019
    Location:187 → 207
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12531.1

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