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ANT1 Ant1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856246, updated on 9-Dec-2024

Summary

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Official Symbol
ANT1
Official Full Name
Ant1p
Primary source
SGD:S000006332
Locus tag
YPR128C
See related
AllianceGenome:SGD:S000006332; FungiDB:YPR128C; VEuPathDB:YPR128C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables adenine nucleotide transmembrane transporter activity. Involved in ATP transport; fatty acid beta-oxidation; and peroxisome organization. Located in peroxisomal membrane. Orthologous to human SLC25A17 (solute carrier family 25 member 17). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ANT1 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (791218..792204, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Ylh47p Neighboring gene pyridoxine 4-dehydrogenase Neighboring gene Scd6p Neighboring gene peptide alpha-N-acetyltransferase complex B subunit NAT3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification and functional reconstitution of the yeast peroxisomal adenine nucleotide transporter. Palmieri L, et al. EMBO J, 2001 Sep 17. PMID 11566870, Free PMC Article
  2. Identification of a peroxisomal ATP carrier required for medium-chain fatty acid beta-oxidation and normal peroxisome proliferation in Saccharomyces cerevisiae. van Roermund CW, et al. Mol Cell Biol, 2001 Jul. PMID 11390660, Free PMC Article
  3. Incorporation of adenine nucleotide transporter, Ant1p, into proteoliposomes facilitates ATP translocation and activation of encapsulated luciferase. Nozawa A, et al. J Biosci Bioeng, 2014 Aug. PMID 24656877
  4. The yeast peroxisomal adenine nucleotide transporter: characterization of two transport modes and involvement in DeltapH formation across peroxisomal membranes. Lasorsa FM, et al. Biochem J, 2004 Aug 1. PMID 15219179, Free PMC Article
  5. The peroxisomal transporter gene ANT1 is regulated by a deviant oleate response element (ORE): characterization of the signal for fatty acid induction. Rottensteiner H, et al. Biochem J, 2002 Jul 1. PMID 12071844, Free PMC Article

See all (40) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Tyrosine phosphorylation by Src within the cavity of the adenine nucleotide translocase 1 regulates ADP/ATP exchange in mitochondria.
    Title: Tyrosine phosphorylation by Src within the cavity of the adenine nucleotide translocase 1 regulates ADP/ATP exchange in mitochondria.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ADP transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ADP transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables adenine nucleotide transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables adenine nucleotide transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in ADP transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ATP transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ATP transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in fatty acid beta-oxidation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fatty acid beta-oxidation IEA
Inferred from Electronic Annotation
more info
  
involved_in fatty acid beta-oxidation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in peroxisome organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in peroxisome organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in peroxisomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in peroxisomal membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in peroxisomal membrane IEA
Inferred from Electronic Annotation
more info
  
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ant1p
NP_015453.1
  • Peroxisomal adenine nucleotide transporter; involved in beta-oxidation of medium-chain fatty acid; required for peroxisome proliferation

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    791218..792204 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184225.1 → NP_015453.1  TPA: Ant1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015453.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W4C5, Q06497
    UniProtKB/TrEMBL
    A6ZX07, B3LK90, B5VTR6, C8ZJF0, N1NW51
    Conserved Domains (1) summary
    pfam00153
    Location:3 → 106
    Mito_carr; Mitochondrial carrier protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q06497.1

Gene LinkOut

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