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YLF2 Ylf2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856372, updated on 4-Jan-2025

Summary

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Official Symbol
YLF2
Official Full Name
Ylf2p
Primary source
SGD:S000001006
Locus tag
YHL014C
See related
AllianceGenome:SGD:S000001006; FungiDB:YHL014C; VEuPathDB:YHL014C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YLF1
Summary
Predicted to enable ATP hydrolysis activity and GTP binding activity. Located in mitochondrion. Orthologous to human OLA1 (Obg like ATPase 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See YLF2 in Genome Data Viewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (76097..77314, complement)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ribosomal 40S subunit protein S20 Neighboring gene Otu2p Neighboring gene UTP--glucose-1-phosphate uridylyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Suppression of yeast RNA polymerase III mutations by the URP2 gene encoding a protein homologous to the mammalian ribosomal protein S20. Hermann-Le Denmat S, et al. J Mol Biol, 1994 Jul 1. PMID 8021936
  2. Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis. Lin YY, et al. Cell, 2009 Mar 20. PMID 19303850, Free PMC Article
  3. Molecular Connectivity of Mitochondrial Gene Expression and OXPHOS Biogenesis. Singh AP, et al. Mol Cell, 2020 Sep 17. PMID 32877643
  4. Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII. Johnston M, et al. Science, 1994 Sep 30. PMID 8091229
  5. RNA-binding and prion domains: the Yin and Yang of phase separation. Gotor NL, et al. Nucleic Acids Res, 2020 Sep 25. PMID 32857852, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTP binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ylf2p
NP_011849.1
  • hypothetical protein; has weak similarity to E. coli GTP-binding protein gtp1; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    76097..77314 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179094.1 → NP_011849.1  TPA: Ylf2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011849.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DKP8, P38746
    UniProtKB/TrEMBL
    A6ZSN8, B3LSA5, C7GIS3, C8ZA52, G2WF53, N1P4Z5
    Conserved Domains (1) summary
    TIGR00092
    Location:16 → 400
    TIGR00092; GTP-binding protein YchF
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38746.1

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