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putative glutamate 5-kinase [ Saccharomyces cerevisiae S288C ]

Gene ID: 856428, updated on 9-Dec-2024

Summary

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Official Full Name
putative glutamate 5-kinase
Primary source
SGD:S000001075
Locus tag
YHR033W
See related
AllianceGenome:SGD:S000001075; FungiDB:YHR033W; VEuPathDB:YHR033W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable glutamate 5-kinase activity. Predicted to be involved in proline biosynthetic process. Located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (175548..176819)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene DNA helicase Neighboring gene Erc1p Neighboring gene Pih1p Neighboring gene GTPase-activating protein NEL1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Prion formation and polyglutamine aggregation are controlled by two classes of genes. Manogaran AL, et al. PLoS Genet, 2011 May. PMID 21625618, Free PMC Article
  2. The ubiquitin-proteasome system regulates meiotic chromosome organization. Yang X, et al. Proc Natl Acad Sci U S A, 2022 Apr 26. PMID 35439061, Free PMC Article
  3. A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria. Lahiri S, et al. PLoS Biol, 2014 Oct. PMID 25313861, Free PMC Article
  4. Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII. Johnston M, et al. Science, 1994 Sep 30. PMID 8091229
  5. Subcellular localization of the yeast proteome. Kumar A, et al. Genes Dev, 2002 Mar 15. PMID 11914276, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables glutamate 5-kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glutamate 5-kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in alpha-amino acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in biological_process ND
No biological Data available
more info
  
involved_in proline biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proline biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
putative glutamate 5-kinase
NP_011898.1
  • hypothetical protein; epitope-tagged protein localizes to the cytoplasm; YHR033W has a paralog, PRO1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    175548..176819
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179163.1 → NP_011898.1  TPA: putative glutamate 5-kinase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011898.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DKY0, P38690, Q66R86
    UniProtKB/TrEMBL
    A6ZST9, G2WFA5, N1P1J6
    Conserved Domains (1) summary
    TIGR01027
    Location:5 → 419
    proB; glutamate 5-kinase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38690.1

Gene LinkOut

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