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HXT5 hexose transporter HXT5 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856496, updated on 9-Dec-2024

Summary

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Official Symbol
HXT5
Official Full Name
hexose transporter HXT5
Primary source
SGD:S000001138
Locus tag
YHR096C
See related
AllianceGenome:SGD:S000001138; FungiDB:YHR096C; VEuPathDB:YHR096C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables D-glucose transmembrane transporter activity; fructose transmembrane transporter activity; and mannose transmembrane transporter activity. Involved in D-glucose transmembrane transport. Located in plasma membrane. Orthologous to human SLC2A6 (solute carrier family 2 member 6) and SLC2A8 (solute carrier family 2 member 8). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See HXT5 in Genome Data Viewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (294669..296447, complement)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Aht1p Neighboring gene hexose transporter HXT1 Neighboring gene Pal2p Neighboring gene Sfb3p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dynamic analysis of cytosolic glucose and ATP levels in yeast using optical sensors. Bermejo C, et al. Biochem J, 2010 Dec 1. PMID 20854260, Free PMC Article
  2. Degradation of the hexose transporter Hxt5p in Saccharomyces cerevisiae. van Suylekom D, et al. Biol Cell, 2007 Jan. PMID 16928197
  3. HXT5 expression is under control of STRE and HAP elements in the HXT5 promoter. Verwaal R, et al. Yeast, 2004 Jul 15. PMID 15282798
  4. HXT5 expression is determined by growth rates in Saccharomyces cerevisiae. Verwaal R, et al. Yeast, 2002 Sep 15. PMID 12210898
  5. Functional analysis of the hexose transporter homologue HXT5 in Saccharomyces cerevisiae. Diderich JA, et al. Yeast, 2001 Dec. PMID 11748728

See all (60) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables D-glucose transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables D-glucose transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables carbohydrate:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables fructose transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables mannose transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-glucose transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in carbohydrate transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fructose transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in hexose transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mannose transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
hexose transporter HXT5
NP_011964.1
  • Hexose transporter with moderate affinity for glucose; induced in the presence of non-fermentable carbon sources, induced by a decrease in growth rate, contains an extended N-terminal domain relative to other HXTs; HXT5 has a paralog, HXT3, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    294669..296447 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179226.1 → NP_011964.1  TPA: hexose transporter HXT5 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011964.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DL46, P38695
    UniProtKB/TrEMBL
    A6ZT04, B3LSL1, C7GLY4, C8Z9N9, E9P9H1, N1P9E5
    Conserved Domains (1) summary
    pfam00083
    Location:89 → 549
    Sugar_tr; Sugar (and other) transporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38695.1

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