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ROF1 Rof1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856582, updated on 4-Jan-2025

Summary

Official Symbol
ROF1
Official Full Name
Rof1p
Primary source
SGD:S000001220
Locus tag
YHR177W
See related
AllianceGenome:SGD:S000001220; FungiDB:YHR177W; VEuPathDB:YHR177W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See ROF1 in Genome Data Viewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (456591..457952)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene N,N-dimethylaniline monooxygenase Neighboring gene Stb5p Neighboring gene NADPH dehydrogenase

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IC
Inferred by Curator
more info
PubMed 

General protein information

Preferred Names
Rof1p
NP_012047.1
  • Putative transcription factor containing a WOPR domain; binds DNA in vitro; similar to C. albicans Wor1p transcription factor that regulates white-opaque switching; overexpression causes a cell cycle delay or arrest

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    456591..457952
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179308.1NP_012047.1  TPA: Rof1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012047.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLC6, P38867
    UniProtKB/TrEMBL
    C7GW82, C8Z9X3, N1P4V2
    Conserved Domains (1) summary
    COG5037
    Location:2249
    TOS9; Gluconate transport-inducing protein [Signal transduction mechanisms / Carbohydrate transport and metabolism]