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RML2 mitochondrial 54S ribosomal protein RML2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856660, updated on 4-Jan-2025

Summary

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Official Symbol
RML2
Official Full Name
mitochondrial 54S ribosomal protein RML2
Primary source
SGD:S000000776
Locus tag
YEL050C
See related
AllianceGenome:SGD:S000000776; FungiDB:YEL050C; VEuPathDB:YEL050C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
uL2m
Summary
A structural constituent of ribosome. Involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL2 (mitochondrial ribosomal protein L2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See RML2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (59670..60851, complement)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Afg1p Neighboring gene H(+)-transporting V1 sector ATPase subunit D Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001137.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional analysis of ribosomal protein L2 in yeast mitochondria. Pan C, et al. J Biol Chem, 1997 Mar 28. PMID 9079633
  2. A mutation in the yeast mitochondrial ribosomal protein Rml2p is associated with a defect in catalase gene expression. Hagerman RA, et al. Mol Cell Biol Res Commun, 2001 Sep. PMID 11529680
  3. A yeast strain defective in oleic acid utilization has a mutation in the RML2 gene. Trotter PJ, et al. Biochim Biophys Acta, 1999 May 18. PMID 10320805
  4. Mitochondrial ribosomal proteins (MRPs) of yeast. Graack HR, et al. Biochem J, 1998 Feb 1. PMID 9445368, Free PMC Article
  5. Identification of novel genes involved in neutral lipid storage by quantitative trait loci analysis of Saccharomyces cerevisiae. Pačnik K, et al. BMC Genomics, 2021 Feb 9. PMID 33563210, Free PMC Article

See all (48) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial translation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitochondrial 54S ribosomal protein RML2
NP_010864.3
  • Mitochondrial ribosomal protein of the large subunit (L2); has similarity to E. coli L2 ribosomal protein; mutant allele (fat21) causes inability to utilize oleate, and induce oleic acid oxidation; may interfere with activity of the Adr1p transcription factor

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    59670..60851 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178865.3 → NP_010864.3  TPA: mitochondrial 54S ribosomal protein RML2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010864.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLK0, P32611
    UniProtKB/TrEMBL
    A6ZQQ1, B3LRW7, B5VH87, C7GXD7, C8Z6U4, G2WCI4, N1P5H1
    Conserved Domains (1) summary
    COG0090
    Location:91 → 387
    RplB; Ribosomal protein L2 [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32611.1

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