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TMN3 Tmn3p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856849, updated on 9-Dec-2024

Summary

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Official Symbol
TMN3
Official Full Name
Tmn3p
Primary source
SGD:S000000915
Locus tag
YER113C
See related
AllianceGenome:SGD:S000000915; FungiDB:YER113C; VEuPathDB:YER113C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in several processes, including intracellular copper ion homeostasis; invasive growth in response to glucose limitation; and pseudohyphal growth. Located in Golgi apparatus. Orthologous to human TM9SF4 (transmembrane 9 superfamily member 4). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See TMN3 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (387932..390052, complement)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene SBF complex DNA-binding subunit SWI4 Neighboring gene U6 snRNA complex subunit LSM4 Neighboring gene Boi2p Neighboring gene Spr6p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001137.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transmembrane nine proteins in yeast and Arabidopsis affect cellular metal contents without changing vacuolar morphology. Hegelund JN, et al. Physiol Plant, 2010 Dec. PMID 20681974
  2. Characterization of a 76 kDa endosomal, multispanning membrane protein that is highly conserved throughout evolution. Schimmöller F, et al. Gene, 1998 Aug 31. PMID 9729438
  3. Control of cellular physiology by TM9 proteins in yeast and Dictyostelium. Froquet R, et al. J Biol Chem, 2008 Mar 14. PMID 18178563
  4. Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast. Dardalhon M, et al. FEMS Yeast Res, 2007 Sep. PMID 17608707, Free PMC Article
  5. The evolutionarily conserved protein Las1 is required for pre-rRNA processing at both ends of ITS2. Schillewaert S, et al. Mol Cell Biol, 2012 Jan. PMID 22083961, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in intracellular copper ion homeostasis IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in invasive growth in response to glucose limitation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in protein localization to membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pseudohyphal growth IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in vacuolar transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus HDA PubMed 
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Tmn3p
NP_011038.3
  • Protein with a role in cellular adhesion and filamentous growth; similar to Emp70p and Tmn2p; member of Transmembrane Nine family with 9 transmembrane segments; localizes to Golgi; induced by 8-methoxypsoralen plus UVA irradiation

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    387932..390052 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179003.3 → NP_011038.3  TPA: Tmn3p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011038.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DM19, P40071
    UniProtKB/TrEMBL
    B3LRM9, C8Z7D1
    Conserved Domains (1) summary
    pfam02990
    Location:78 → 663
    EMP70; Endomembrane protein 70
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40071.1

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