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Ir75b Ionotropic receptor 75b [ Drosophila melanogaster (fruit fly) ]

Gene ID: 8673994, updated on 9-Dec-2024

Summary

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Official Symbol
Ir75bprovided by FlyBase
Official Full Name
Ionotropic receptor 75bprovided by FlyBase
Primary source
FLYBASE:FBgn0261402
Locus tag
Dmel_CG42643
See related
AllianceGenome:FB:FBgn0261402
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
75b; CG14586; CG14586-B; CG42643; DmelIR75b; Dmel\CG42643; Ir75abc; IR75abc; IR75b
Summary
Predicted to enable ligand-gated monoatomic ion channel activity. Involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Is expressed in antennal coeloconic sensillum ac3. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Ir75b in Genome Data Viewer
Location:
75A2-75A2; 3-45 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17818073..17820193, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17811173..17813293, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Cln3 Neighboring gene Ionotropic receptor 75a Neighboring gene Ionotropic receptor 75c Neighboring gene Glycine receptor Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Odor-regulated oviposition behavior in an ecological specialist. Álvarez-Ocaña R, et al. Nat Commun, 2023 May 26. PMID 37236992, Free PMC Article
  2. Molecular reconstruction of recurrent evolutionary switching in olfactory receptor specificity. Prieto-Godino LL, et al. Elife, 2021 Oct 22. PMID 34677122, Free PMC Article
  3. Evolution of Acid-Sensing Olfactory Circuits in Drosophilids. Prieto-Godino LL, et al. Neuron, 2017 Feb 8. PMID 28111079
  4. Olfactory receptor pseudo-pseudogenes. Prieto-Godino LL, et al. Nature, 2016 Nov 3. PMID 27776356, Free PMC Article
  5. Olfactory receptor-dependent receptor repression in Drosophila. Mika K, et al. Sci Adv, 2021 Aug. PMID 34362730, Free PMC Article

See all (44) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ligand-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
enables ligand-gated monoatomic ion channel activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of chemical stimulus involved in sensory perception IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
ionotropic receptor 75b
Names
CG42643-PA
Ir75b-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    17818073..17820193 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001144494.2 → NP_001137966.2  ionotropic receptor 75b [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001137966.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1S6EMU4, B7Z069
    Conserved Domains (2) summary
    pfam00060
    Location:343 → 585
    Lig_chan; Ligand-gated ion channel
    cl21456
    Location:253 → 553
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B7Z069 B7Z069

Gene LinkOut

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