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nrdA ribonucleotide-diphosphate reductase subunit alpha [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 877716, updated on 24-Aug-2024

Summary

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Gene symbol
nrdA
Gene description
ribonucleotide-diphosphate reductase subunit alpha
Locus tag
PA1156
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (1251418..1254309, complement)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene ribonucleotide-diphosphate reductase subunit beta Neighboring gene two-component response regulator Neighboring gene two-component sensor

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Shift in ribonucleotide reductase gene expression in Pseudomonas aeruginosa during infection. Sjöberg BM, et al. Infect Immun, 2011 Jul. PMID 21502590, Free PMC Article
  2. Ribonucleotide reductase modularity: Atypical duplication of the ATP-cone domain in Pseudomonas aeruginosa. Torrents E, et al. J Biol Chem, 2006 Sep 1. PMID 16829681
  3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. There is a shift in nrd expression during infection, with induction of nrdJ and nrdD expression and concomitant repression of nrdA transcription.
    Title: Shift in ribonucleotide reductase gene expression in Pseudomonas aeruginosa during infection.
  2. NrdA and NrdB proteins form an extraordinarily tight complex with a suggested alpha4beta4 composition for ribonucleotide reductase
    Title: Ribonucleotide reductase modularity: Atypical duplication of the ATP-cone domain in Pseudomonas aeruginosa.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by PseudoCAP

Component Evidence Code Pubs
part_of ribonucleoside-diphosphate reductase complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ribonucleotide-diphosphate reductase subunit alpha
NP_249847.1
  • Product name confidence: class 2 (High similarity to functionally studied protein)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    1251418..1254309 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_249847.1 ribonucleotide-diphosphate reductase subunit alpha [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_249847.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A3M5DRQ5
    Conserved Domains (1) summary
    PRK07207
    Location:2 → 963
    PRK07207; ribonucleoside-diphosphate reductase subunit alpha
Nucleotide Protein
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