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rpoA DNA-directed RNA polymerase subunit alpha [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 881813, updated on 11-Sep-2024

Summary

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Gene symbol
rpoA
Gene description
DNA-directed RNA polymerase subunit alpha
Locus tag
PA4238
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (4754423..4755424, complement)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene catalase Neighboring gene 50S ribosomal protein L17 Neighboring gene 30S ribosomal protein S4 Neighboring gene 30S ribosomal protein S11

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Phage-Encoded N-Acetyltransferase Rac Mediates Inactivation of Pseudomonas aeruginosa Transcription by Cleavage of the RNA Polymerase Alpha Subunit. Ceyssens PJ, et al. Viruses, 2020 Sep 2. PMID 32887488, Free PMC Article
  2. Activation defects caused by mutations in Escherichia coli rpoA are promoter specific. Gussin GN, et al. J Bacteriol, 1992 Aug. PMID 1629175, Free PMC Article
  3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The Phage-Encoded N-Acetyltransferase Rac Mediates Inactivation of Pseudomonas aeruginosa Transcription by Cleavage of the RNA Polymerase Alpha Subunit.
    Title: The Phage-Encoded N-Acetyltransferase Rac Mediates Inactivation of Pseudomonas aeruginosa Transcription by Cleavage of the RNA Polymerase Alpha Subunit.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by PseudoCAP

Process Evidence Code Pubs
acts_upstream_of_or_within DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
DNA-directed RNA polymerase subunit alpha
NP_252928.1
  • Product name confidence: class 2 (High similarity to functionally studied protein)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    4754423..4755424 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_252928.1 DNA-directed RNA polymerase subunit alpha [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_252928.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O52760
    Conserved Domains (1) summary
    PRK05182
    Location:6 → 315
    PRK05182; DNA-directed RNA polymerase subunit alpha; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O52760.2

Gene LinkOut

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Molecular Biology Databases
Research Materials