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rseA anti-sigma E factor RseA [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 885196, updated on 11-Dec-2020

Summary

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Gene symbol
rseA
Gene description
anti-sigma E factor RseA
Locus tag
Rv1222
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (1365344..1365808)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene methyltransferase Neighboring gene ECF RNA polymerase sigma factor SigE Neighboring gene serine protease HtrA Neighboring gene Sec-independent protein translocase protein TatB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Assessing the role of Rv1222 (RseA) as an anti-sigma factor of the Mycobacterium tuberculosis extracytoplasmic sigma factor SigE. Boldrin F, et al. Sci Rep, 2019 Mar 14. PMID 30872756, Free PMC Article
  2. Novel mechanism of gene regulation: the protein Rv1222 of Mycobacterium tuberculosis inhibits transcription by anchoring the RNA polymerase onto DNA. Rudra P, et al. Nucleic Acids Res, 2015 Jul 13. PMID 25999340, Free PMC Article
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Assessing the role of Rv1222 (RseA) as an anti-sigma factor of the Mycobacterium tuberculosis extracytoplasmic sigma factor SigE.
    Title: Assessing the role of Rv1222 (RseA) as an anti-sigma factor of the Mycobacterium tuberculosis extracytoplasmic sigma factor SigE.
  2. The study demonstrates that the positively charged C-terminus tail of Rv1222 is responsible for anchoring RNA polymerase (RNAP)on DNA, hence the protein slows down the movement of RNAP along the DNA during transcription elongation.
    Title: Novel mechanism of gene regulation: the protein Rv1222 of Mycobacterium tuberculosis inhibits transcription by anchoring the RNA polymerase onto DNA.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
anti-sigma E factor RseA
NP_215738.1
  • A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004 PMID:14766927).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    1365344..1365808
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215738.1 anti-sigma E factor RseA [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215738.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    L0T905
    UniProtKB/TrEMBL
    Q79FQ8
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
L0T905.1

Gene LinkOut

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