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hisE phosphoribosyl-ATP pyrophosphatase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888671, updated on 6-Oct-2023

Summary

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Gene symbol
hisE
Gene description
phosphoribosyl-ATP pyrophosphatase
Locus tag
Rv2122c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
irg1
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Genomic context

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Sequence:
NC_000962.3 (2380663..2380944, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene integral membrane protein Neighboring gene ATP phosphoribosyltransferase Neighboring gene PPE family protein PPE37 Neighboring gene methionine synthase Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis. Javid-Majd F, et al. Acta Crystallogr D Biol Crystallogr, 2008 Jun. PMID 18560150, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
phosphoribosyl-ATP pyrophosphatase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2380663..2380944 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_177860.1 phosphoribosyl-ATP pyrophosphatase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for YP_177860.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2I7W8J6
    Conserved Domains (1) summary
    cd11547
    Location:8 → 93
    NTP-PPase_HisE; Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Mycobacterium tuberculosis phosphoribosyl-ATP pyrophosphohydrolase (HisE or PRATP-PH) and its bacterial homologs
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WMM9.1

Gene LinkOut

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Molecular Biology Databases
Research Materials